Obesity is a serious health problem of 21st century. Around 1 billion adults are overweight and more than 300 million people found to be obese globally. In fact 2.6 die per year due obesity thus it has now become major reason morbidity mortality. line this few novel pyrazole derivatives (Z)-3-(4-subtituted phenyl)-2-(3, 5-dimethyl-1H-pyrazol-1-yl)-1-phenylprop-2-en-1-one (4a-f) were synthesized...

Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and an...

starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. from the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. reaction of compound 15 with diazomethane gave i-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. the antibacterial and antif...

By using the dimethyl chloronium salt [(CH 3 ) 2 Cl] + [Al(OTeF 5 4 ] ? in combination with weakly coordinating pentafluoro-orthotelluratoaluminate anion it is possible to quaternize phosphorus atom of a series ? ,? -phosphinines one step.

2-(Diphenyl-thio-phosphino)dimethyl-amino-methyl-ferrocene is a key inter-mediate in the synthesis of various ferrocenyl ligands. During one such synthesis, the title compound, [Fe(C(5)H(5))(C(20)H(22)NPS)](C(12)H(10)PS(2)), was isolated as a by-product. It is built up by association of (2-(diphenyl-phosphino)ferrocen-yl)meth-yl)dimethyl-ammonium cations and diphenyl-phosphino dithio-ate anions...