Minor histocompatibility (H) antigens crucially affect the outcome of human leukocyte antigen (HLA)-identical allogeneic stem cell transplantation (SCT). To understand the basis of alloimmune responses against minor H antigens, identification of minor H peptides and their antigenicity-determining mechanisms is essential. Here we report the identification of HA-3 and its encoding gene. The HA-3 ...

BACKGROUND Hydroxyapatite (HA) is the main mineral component of the tooth structure, which exhibits considerable biological behavior and its incorporation might improve microhardness of dental materials. Microhardness of restorative materials, like glass-ionomer, is critical for the clinical longevity of restorations. The aim of this study was to evaluate the microhardness of two glass-ionomers...

A field experiment was conducted at the Agronomy Field Laboratory, Bangladesh Agricultural University, Mymensingh during the period from July to December 2011 to evaluate the effect of variety and placement method of urea super granule (USG) on the yield performance of T. aman rice varieties. The experiment consisted of three aman rice varieties viz., Pajam, BR11, BRRI dhan40 and four placement...

Adoptive transfer of antigen-specific T cells is an attractive strategy for the treatment of hematologic malignancies. It has been shown that T cells recognizing minor histocompatibility antigens (mHag) selectively expressed on hematopoietic cells mediate antileukemic reactivity after allogeneic stem cell transplantation. However, large numbers of T cells with defined specificity are difficult ...

Materials Sodium form of hyaluronic acid (HA, MW, 10 kDa) was a gift of Kolon Life Science, Korea. EDC.HCl (99%) and N-Hydroxy succinimide (NHS, 99%) were purchased from Shanghai Medeep Co., Ltd. Monostearin (glycerol α-monostearate, GMS), Sodium deoxycholate (DOC) and fluorescein isothiocyanate (FITC) were purchased from Solarbio (Beijing, China). Doxorubicin hydrochloride (DOX) was supplied b...

Allogeneic bone marrow transplantation (BMT) is a common treatment of hematologic malignancies. Recurrence of the underlying malignancy is a major cause of treatment failure. Donor-derived cytotoxic T lymphocytes (CTLs) specific for patients' minor histocompatibility antigens (mHags) play an important role in both graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) reactivities. mH...

Hyperthermia-induced hyperventilation has been proposed to be a human thermolytic thermoregulatory response and to contribute to the disproportionate increase in exercise ventilation (VE) relative to metabolic needs during high-intensity exercise. In this study it was hypothesized that VE would adapt similar to human eccrine sweating (E(SW)) following a passive heat acclimation (HA). All partic...

Jelölje [n] az {1, 2, ..., n} halmazt, 2[n] pedig [n] összes részhalmazát. Vegyünk egy F ⊂ 2[n] halmazrendszert. |F| maximumát keressük, ha bármely r részhalmaz metszete legalább s elem¶, és bármely ` különböz® halmaz metszete legfeljebb t elem¶, a paraméterek különféle vásztása mellett. Az r = 2, s = t = 1 esetben, tehát amikor bármely két halmaz metszete nemüres, de bármely ` különböz® halmaz...

A new soil extractant (HA) with the ability to extract NH4, NO3, and P from soil was developed and tested against 32 soils, which varied greatly in clay content, organic carbon (C), and soil pH. The extractant (HA) eliminates the need for separate phosphorus (P) extractants for acid and calcareous soils and maintains the extract pH, on average, within one unit of the soil pH. The extractant is ...