The application of cross sectional echocardiography and pulsed Doppler ultrasound to the management of symptomatic neonates with suspected congenital heart disease was studied in 96 consecutive cases. The ability of echocardiography to establish a complete and accurate diagnosis and a correct management plan was evaluated. Sequential segmental analysis of data from cardiac catheterisation and n...

The casein kinase 1 (CK1) plays an important role in various biological processes by phosphorylating its target proteins. In this study, we demonstrate that CK1γ1 inhibits RNA virus-mediated activation of retinoic acid-inducible gene I (RIG-I) signaling by affecting the stability of NF-κB subunit p65. First, we found that ectopic expression of CK1γ1 inhibits RIG-I pathway-mediated activation of...

To test the canine reservoir hypothesis of extraintestinal pathogenic Escherichia coli (ExPEC), 63 environmental canine fecal deposits were evaluated for the presence of ExPEC by a combination of selective culturing, extended virulence genotyping, hemagglutination testing, O serotyping, and PCR-based phylotyping. Overall, 30% of canine fecal samples (56% of those that yielded viable E. coli) co...

Mammalian signal peptides can be used to aid in the secretion of mammalian proteins that are normally not secreted. By inactivating signals normally present in the 3' UTRs of mRNAs encoding proteins that are normally not secreted from mammalian cells, the proportion of such mRNA molecules directed to free and cytoskeletal bound polysomes can be reduced. Inventors: Hesketh; John Edward (Newcastl...

Exploiting the presence of kilohertz quasi-periodic oscillations (QPOs) in the timing power spectrum, we find that the soft x-ray emission of the neutron-star X-ray binary and atoll source 4U 1636-536 modulated at the QPO frequency lags behind that of the hard x-ray emission. Emission in the 3.8–6.4 keV band is delayed by 25.0±3.3 μs relative to the 9.3–69 keV band. The delay increases in magni...

We present the results of a study with the Swift Burst Alert Telescope in the 14 – 195 keV range of the long-term variability of 5 low mass X-ray binaries with reported or suspected super-orbital periods — 4U 1636-536, 4U 1820-303, 4U 1916-053, Cyg X-2 and Sco X-1. No significant persistent periodic modulation was detected around the previously reported periods in the 4U 1916-053, Cyg X-2 or Sc...

The nutritive value of spontaneously fermented brown rice flour medida, a Sudanese cereal thin porridge, is low. This study was carried out to improve the nutritional quality of medida. The flour was soaked and malted at 30◦C to optimise the protein content. Flour malted for two days had the highest protein content. Skim milk was added to the malted brown rice flour medida and fermented using B...

The significance of endocervical cylindrical cells (EC) as a criterion of sample adequacy has been established on 1,000 patients by comparing VCE smears (vaginal, cervical, endocervical) with or without EC in relation to prevalence of abnormal cells, prevalence of histological diagnosed lesions and sensitivity and negative predictive value of Pap smear, as well as by comparison of negative find...

The application of cross sectional echocardiography and pulsed Doppler ultrasound to the management of symptomatic neonates with suspected congenital heart disease was studied in 96 consecutive cases. The ability of echocardiography to establish a complete and accurate diagnosis and a correct management plan was evaluated. Sequential segmental analysis of data from cardiac catheterisation and n...

relative abundances of HI and H2 in natural terrestrial hydrogen, it is now necessary to know the past history of the hydrogen sample used by the observer and some of the discrepancies reported may be due to differences in the samples used.3 In addition to the electrolysis method for fractionating water, the distillation method could also be utilized by the unidirectional evaporation of a satur...