The aim of the present study was to investigate whether the four guanosines (4G)/five guanosines (5G) polymorphism in the gene coding for plasminogen activator inhibitor-1 (PAI-1) affects the clinical features of primary nephrotic syndrome (PNS). A cohort of 200 biopsy-diagnosed PNS patients was studied, with 40 healthy subjects as controls. The PAI-1 gene polymorphism was detected by polymeras...

Fifth generation (5G) cellular networks will be comprised of millions of connected devices like wearable devices, Androids, iPhones, tablets and the Internet of Things (IoT) with a plethora of applications generating requests to the network. The 5G cellular networks need to cope with such sky-rocketing traffic requests from these devices to avoid network congestion. As such, cloud radio access ...

To cope with the growing demand for wireless data and to extend service coverage, future 5G networks will increasingly rely on the use of low powered nodes to support massive connectivity in diverse set of applications and services [1]. To this end, virtualized and mass-scale cloud architectures are proposed as promising technologies for 5G in which all the nodes are connected via a backhaul ne...

PURPOSE Plasminogen activator inhibitor-1 (PAI-1) plays an important role in cancer invasion and metastasis. A common polymorphism (4G/5G) in the promoter region of the PAI-1 gene has been reported to influence transcription and plasma levels of PAI-1. We evaluated the association between PAI-1 4G/5G polymorphism and breast cancer survival in a population-based cohort of breast cancer patients....

The fifth-generation mobile networks (5G) will not only enhance mobile broadband services, but also enable connectivity for a massive number of Internet-of-Things devices, such as wireless sensors, meters or actuators. Thus, 5G is expected to achieve a 1000-fold or more increase in capacity over 4G. The use of the millimeter-wave (mmWave) spectrum is a key enabler to allowing 5G to achieve such...

Asthma is characterised by chronic airway inflammation and remodelling, which can be (partially) suppressed by inhaled corticosteroids (ICSs). Plasminogen activator inhibitor-1, encoded by the SERPINE1 gene, is the key inhibitor of the plasminogen activator system, which affects tissue repair and remodelling. We studied associations between a functional SERPINE1 -675 4G/5G promoter polymorphism...

5G mobile communication networks are emerging in order to cover the extreme needs for high data rates for delivering multimedia data to mobile communication users. The required bandwidth may be found if millimeter wave bands are fully employed for the establishment of such cellular systems. In this Book Chapter the propagation issues for 5G mobile communication systems are rigorously analyzed a...

This study investigates how rearing under conditions of hypergravity affects amphibian development, Xotx2 and Xag1 gene expression and apoptosis. Uncleaved Xenopus laevis eggs 20 min after insemination, 2 cell stage embryos, and gastrula stage embryos were raised at 2G and 5G, while controls were raised in normal gravity. Apoptosis in brain and eye inner structures of hatching embryos was score...

In the millimeter-wave bands towards 5G, human exposure to radio frequency (RF) electromagnetic field (EMF) is evaluated in terms of free space power density, rather than specific absorption rate. Maximum power density emitted by 5G user equipment should not exceed the power density limits set by relevant regulatory guidelines. In this paper, we provide upper bounds of maximum power density of ...

We investigated the association between plasminogen activator inhibitor-1 (PAI-1) polymorphisms and plasma PAI-1 level with sepsis in severely burned patients. A total of 182 patients with burn areas lager than 30% of the body surface area were enrolled in this study. Peripheral blood samples were obtained from 103 patients with sepsis (sepsis group) and 79 patients without sepsis (control grou...