Recent studies have demonstrated significant genetic and phenotypic correlation underlying the clustering of traits involved in the multiple metabolic syndrome (MMS). The aim of this study was to identify chromosomal regions contributing to MMS-related traits represented by composite factors derived from factor analysis. Data from the National Heart, Lung, and Blood Institute (NHLBI) Family Hea...

PURPOSE Malignant melanoma's (MM) incidence is rising faster than that of any other cancer in the US and the overall survival at 5 years is less than 10%. B cell associated protein 31 (BAP31) is overexpressed in most MMs and might be a promising target for immunotherapy of this disease. EXPERIMENTAL DESIGN Firstly, we investigated the expression profiles of human BAP31 (hBAP31) and mouse BAP3...

Mouse fibroblasts, deficient in DNA polymerase ß (ß-pol), are hypersensitive to monofunctional DNA methylating agents such as methyl methanesulfonate (MMS). Both wild-type, and in particular repair deficient ßpol null cells, are highly sensitized to the cytotoxic effects of MMS by 4-amino-1,8naphthalimide (4-AN), an inhibitor of poly(ADP-ribose) polymerase (PARP) activity. Experiments with sync...

Copper Institute, Industrial Informatics department, is developing and applying network real time process monitoring and control systems. The kernel of those systems is the microprocessor measuring station MMS. In hardware and software point of view, MMS is a type of PLC (programmable logic controller) with some of local and remote functional possibilities. In monitoring and control of technolo...

Discrete magnetic metamaterials (MMs) comprised, e.g. of periodically arranged nonlinear split-ring resonators (SRRs), may support highly localized excitations in the form of discrete breathers (DBs) [1]. In practice, the SRRs can become nonlinear by the insertion of nonlinear electronic components into their slits [2]. Recently, a novel MM comprised of two types of SRRs was investigated theore...

Moyamoya disease is a cerebrovascular disorder with unknown cause characterized by the occlusion of the bilateral internal carotid arteries (ICA) and proximal segments of ICA.1,2 On the other hand, moyamoya syndrome (MMS) is a rare form of this condition with underlying several pathologies including hematologic disorders, congenital syndromes, vascular malformations or vasculitis after irradiat...

Populations on islands often exhibit lower levels of genetic variation and ecomorphological divergence compared to their mainland relatives. While phenotypic differentiation in characters, such as size or shape among insular organisms, has been well studied, insular differentiation in quantitative reproductive traits involved in chemical communication has received very little attention to date....

The paper describes the results of a project specifically designed to evaluate the utility of Prolog for industrial software production. The project was financed by the IBM Canada Laboratory and the work was done by the University of Montréal in collaboration with the Computer Research Institute of Montréal (CRIM). Initially, the objective was to compare the industrial implementation of a telec...

STUDY OBJECTIVES Obstructive sleep apnea-hypopnea (OAH) diagnosis in children is based on the quantification of flow and respiratory effort (RE). Pulse transit time (PTT) is one validated tool to recognize RE. Pattern analysis of mandibular movements (MM) might be an alternative method to detect RE. We compared several patterns of MM to concomittant changes in PTT during OAH in children with ad...

Mitochondrial DNA (mtDNA) encodes proteins essential for ATP production. Mutant variants of the mtDNA polymerase cause mutagenesis that contributes to aging, genetic diseases, and sensitivity to environmental agents. We interrogated mtDNA replication in Saccharomyces cerevisiae strains with disease-associated mutations affecting conserved regions of the mtDNA polymerase, Mip1, in the presence o...