The purposes of the present studies were to test the hypotheses that lower dosages of oral pyruvate ingestion would increase blood pyruvate concentration and that the ingestion of a commonly recommended dosage of pyruvate (7 g) for 7 days would enhance performance during intense aerobic exercise in well-trained individuals. Nine recreationally active subjects (8 women, 1 man) consumed 7, 15, an...

During the spaceflight under weightlessness condition, human's brain function may be affected by the changes of physiological effects along with the distribution of blood and body fluids to the head. This variation of brain function will influence the performance of astronauts and therefore create possible harm to flight safety. This study employs 20 male subjects in a 7-day-6° head-down tilted...

Myelodysplastic syndrome (MDS) refers to a group of haematological, monoclonal disorders. A 50-year-old woman was diagnosed with MDS 5q deletion syndrome [del(5q)], becoming dependent on blood transfusion after long-term treatment with cytotoxic drugs for chronic scleritis. Lenalidomide therapy (10 mg/day) led to profound pancytopaenia, followed by recovery of her blood cell counts. A cytogenet...

OBJECTIVES In contrast to peripheral nerves, central neurons do not regrow spontaneously after injury. Our previous studies showed that transplantation of degenerating peripheral nerves or their extracts can induce regeneration in the injured central nervous system. Non-predegenerated nerves show much weaker neurotrophic activity. The aim of the present work was to examine quantitatively and qu...

Patients with acute kidney injury (AKI) have increased mortality; data suggest that the duration, not just severity, of AKI predicts increased mortality. Animal models suggest that AKI is a multisystem disease that deleteriously affects the lungs, heart, brain, intestine, and liver; notably, these effects have only been examined within 48 h, and longer term effects are unknown. In this study, w...

OBJECTIVE We characterized breastfeeding concerns from open-text maternal responses and determined their association with stopping breastfeeding by 60 days (stopping breastfeeding) and feeding any formula between 30 and 60 days (formula use). METHODS We assessed breastfeeding support, intentions, and concerns in 532 expectant primiparas and conducted follow-up interviews at 0, 3, 7, 14, 30, a...

BACKGROUND The frequency of hematuria and proteinuria was assessed in terms of the existence of glomerular disorders. METHODS Fifty-five patients with asymptomatic microscopic hematuria, in whom no urological disorders were recognized, were used in this study. The frequency of hematuria and proteinuria was assessed by self-test of the first voided urine in the morning with urinary dipsticks f...

Introduction: The aim of this abstract is to acquaint the reader with the major geochemical and geochronological properties of lunar rocks formed or affected by impact events, and thus how these rocks constrain lunar bombardment history, with particular emphasis on constraints upon the proposed Lunar Cataclysm or Late Heavy Bombardment [1]. To this end, the focus is on clast-poor impact melt ro...

The study was undertaken to evaluate (a) the reliability of pedometer data and reactivity of children to wearing a pedometer, (b) the effectiveness of a missing data replacement procedure, and (c) the validity of the Leisure Time Exercise Questionnaire (LTEQ). Six days of pedometer data were collected from 299 middle-school children, followed by administration of the LTEQ. Six days of pedometer...

Background The killing of women by intimate partners (also known as intimate female homicide or intimate femicide) is the most extreme form and consequence of violence against women. Globally, gender differences are found in homicide patterns. Men are at greater risk of being killed than women and this is mainly done by other men. Women, on the other hand, are primarily killed by the opposite g...