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We recently showed that interleukin-9 (IL-9), a Th2 cytokine, promotes IL-5-mediated rejection of allografts in mice. This observation led us to investigate the functional link between IL-9 and IL-5 production during alloreactive T cell responses in vitro and in vivo. Firstly, we found that IL-9 was produced by alloreactive Th2 cells, and IL-9 mRNA was detected in skin allograft during Th2-type...
Introduction. Bladder cancer (BCa) is one the most common urinary system malignancies and approximately quarter of diagnosis invasive muscle-invasive BCa. Accumulating evidence revealed that keratin 17 (KRT17) closely related to prognosis progression various tumors including a recent study also implying potential role KRT17 in However, specific BCa remains be elucidated. Material methods. The e...
Bladder cancer is one of the most commonly diagnosed cancers worldwide, especially in males. Current therapeutic interventions, including surgery, radiation therapy, chemotherapy, and immunotherapy, have not been able to improve clinical outcome bladder patients with satisfaction. Recombinant human arginase (rhArg, BCT-100) a novel agent great anticancer effects on arginine-auxotrophic tumors. ...
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