نتایج جستجو برای: 962 snps average observed heterozygosity

تعداد نتایج: 1241553  

2014
Bing-Bing Liu Bin Tian Hui Ma Zhi-Qiang Lu Qiang Qiu Kang-Shan Mao Jian-Quan Liu

UNLABELLED PREMISE OF THE STUDY A set of expressed sequence tag (EST) microsatellite markers were developed and characterized using next-generation sequencing technology for the Chinese genus Ostryopsis (Betulaceae). • METHODS AND RESULTS A total of 38 high-quality simple sequence repeat (SSR) primers were identified, of which 15 could be successfully amplified. Subsequently, we selected 8...

A. Taheri Mirghaed E. Shirzad J. Taghavi M. M. Nayerani S. Mohamadian S. Rezavani Gilkolaei S. Rouhollahi

 Population genetic structure of Vimba vimba persa was investigated using microsatellite markers from 40 regions along the Iranian coastline of the Southern Caspian Sea (Anzali lagoon and Havigh River in Gilan province, BabolRoud River in Mazandaran province and GorganRoud River in Golestan province). Genomic DNA from 121 specimens was extracted from fin tissue by the Phenol-Chlorophorm method ...

A. Taheri Mirghaed , E. Shirzad , J. Taghavi M., M. Nayerani, S. Mohamadian, S. Rezavani Gilkolaei , S. Rouhollahi,

 Population genetic structure of Vimba vimba persa was investigated using microsatellite markers from 40 regions along the Iranian coastline of the Southern Caspian Sea (Anzali lagoon and Havigh River in Gilan province, BabolRoud River in Mazandaran province and GorganRoud River in Golestan province). Genomic DNA from 121 specimens was extracted from fin tissue by the Phenol-Chlorophor...

Journal: :Genetics 1990
N Takahata M Nei

To explain the long-term persistence of polymorphic alleles (trans-specific polymorphism) at the major histocompatibility complex (MHC) loci in rodents and primates, a computer simulation study was conducted about the coalescence time of different alleles sampled under various forms of selection. At the same time, average heterozygosity, the number of alleles in a sample, and the rate of codon ...

2013
Alexander Gusev Gaurav Bhatia Noah Zaitlen Bjarni J. Vilhjalmsson Dorothée Diogo Eli A. Stahl Peter K. Gregersen Jane Worthington Lars Klareskog Soumya Raychaudhuri Robert M. Plenge Bogdan Pasaniuc Alkes L. Price

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we use variance components to quantify the heritability explained by all SNPs at known GWAS loci in...

Journal: :Current Biology 2016
Fan Liu Merel A. Hamer Joris Deelen Japal S. Lall Leonie Jacobs Diana van Heemst Peter G. Murray Andreas Wollstein Anton J.M. de Craen Hae-Won Uh Changqing Zeng Albert Hofman André G. Uitterlinden Jeanine J. Houwing-Duistermaat Luba M. Pardo Marian Beekman P. Eline Slagboom Tamar Nijsten Manfred Kayser David A. Gunn

Looking young for one's age has been a desire since time immemorial. This desire is attributable to the belief that appearance reflects health and fecundity. Indeed, perceived age predicts survival [1] and associates with molecular markers of aging such as telomere length [2]. Understanding the underlying molecular biology of perceived age is vital for identifying new aging therapies among othe...

2007
Pedro Javier Azor Mercedes Valera María Dolores Gómez Félix Goyache Antonio Molina

To assist in selection schemes we carried out the first genetic characterization of the Spanish Trotter horse (Trotador Español). We used 16 microsatellite markers to genotype 40 unrelated Spanish trotters, 25 native Balearic horses (11 Menorquina and 14 Mallorquina horses) and 32 Andalusian horses. The observed heterozygosity for the Spanish Trotters was 0.647 ± 0.037 and the expected heterozy...

2016
Ana González-Robles Antonio J. Manzaneda Jesús M. Bastida Nick Harvey Rafael Jaime Teresa Salido Luisa M. Martínez Ana Fernández-Ocaña Julio M. Alcántara Pedro J. Rey

PREMISE OF THE STUDY Microsatellite primers were developed to characterize and evaluate patterns of genetic diversity and structure in the endangered Mediterranean shrub Ziziphus lotus (Rhamnaceae). METHODS AND RESULTS Twenty microsatellite primers were developed for Z. lotus, of which 14 were polymorphic. We evaluated microsatellite polymorphism in 97 specimens from 18 Spanish and seven Moro...

Journal: :Animal genetics 2003
M A Cronin J C Patton N Balmysheva M D MacNeil

Genetic variation at seven microsatellite DNA loci was quantified in 19 herds of wild caribou and domestic reindeer (Rangifer tarandus) from North America, Scandinavia and Russia. There is an average of 2.0-6.6 alleles per locus and observed individual heterozygosity of 0.33-0.50 in most herds. A herd on Svalbard Island, Scandinavia, is an exception, with relatively few alleles and low heterozy...

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