Because ascorbic acid (AA) is concentrated in synaptic vesicles containing glutamic acid, we hypothesized that AA might act as a neurotransmitter. Because AA is an antioxidant, it might therefore inhibit nitric oxidergic (NOergic) activation of luteinizing hormone-releasing hormone (LH-RH) release from medial basal hypothalamic explants by chemically reducing NO. Cell membrane depolarization in...

We investigated the effects of hypotonic saline-induced modifications of extracellular volume and sodium handling on the renal and metabolic response to amino acids (AA). Renal hemodynamics (Inutest, p-aminohippurate clearance), plasma AA, and glucagon levels, as well as urea and sodium excretion, were studied in seven adult volunteers infused for 2 h, on six separate occasions, according to th...

purpose : to determine add power (ap) and amplitude of accommodation (aa) in a sample of iranian population and its relationship with refractive errors methods : this cross-sectional study enrolled people of 35-70 years old by simple random sampling. exclusion criteria were myopia or hyperopia over 6 diopter (d) and astigmatism more than 0.75 d. those with a history of eye disorders and taking ...

In this paper, the carbon paste electrode (CPE) is modified using an ionic liquid (1-Butyl-3-methylimidazolium tetrafluoroborate, [BMIM]BF4) and the cis-dioxo-bis[3-methoxy-2,2-dimethylpropanediamine] molybdenum(VI) complex (cis-[Mo(O)2L]). In order to study of the electrochemical behavior of ascorbic acid (AA) and dopamine (DA) at the surface of the prepared CPEs, the differential pulse and cy...

Increased activity of mesolimbic dopaminergic system within ventral tegmental area (VTA) due to nicotine results in psychologic dependence. It has been argued that function of dopamine receptors could by affected by ascorbic acid (AA). Furthermore, AA can decrease the withdrawal syndrome signs in addicted animals and may postpone the development of nicotine dependence. In the present study, the...