A paradoxical microcirculatory constriction has been observed in hearts of patients with ischemia, secondary to coronary stenosis. Here, using the isolated mouse heart (Langendorff), we examined the mechanism of this response, assuming involvement of nitric oxide (NO) and endothelin-1 (ET-1) systems. Perfusion pressure was maintained at 65 mmHg for 70 min (protocol 1), or it was reduced to 30 m...

higher MetHb values in the presence of HbF. For MetHb concentrations of 15% or less, i.e., values most likely to be encountered clinically with NO therapy, the Corning 270, in agreement with the study carried out previously (5), was unaffected by the presence of HbF in the umbilical cord sample (P 5 0.7380). By contrast, the Chiron 800 showed a constant error to significantly higher MetHb (P 5 ...

ditional Chinese medicine as a cancer treatment and also as an insecticide for hundreds of years. In recent years, its xylem extract has been used in the clinical treatment of rheumatoid arthritis, skin disorders, male-fertility control, and other inflammatory and autoimmune diseases. In previous papers, we have reported the isolation of some antiHIV agents, triptonines A and B, along with seve...

The main objective of this project was to implement the real-time soft shadow volume method proposed by Ulf Assarsson and Thomas Akenine-Möller in their SIGGRAPH 2003 paper [1]. The original method is proposed as a hardware implementation. However due to time constraints, the implementation in this project does not employ a graphics accelerator card for the soft shadow rendering. Fortunately, t...