To the Editor: Kaposi’s varicelliform eruption (KVE) is a distinct viral skin disease which is characterized by disseminated vesiculopustules and erosions superimposed on the preexisting dermatosis. It is mostly caused by herpes simplex virus (HSV) type 1 or 2 and rarely by vaccine‐virus or Coxsackie A16 virus. The KVE is normally described in atopic dermatitis (AD), but also observed in associ...

Darier disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare autosomal dominant genodermatosis. It is clinically manifested by hyperkeratotic papules primarily affecting seborrheic areas on the head, neck and thorax, with less frequent involvement of the oral mucosa. When oral manifestations are present, they primarily affect the palatal and alveolar mucosa, are ...

IgA pemphigus is a rare neutrophilic acantholytic skin disorder with only approximately 70 cases reported in the indexed literature to date. Here we describe two patients with IgA pemphigus (subcorneal pustular dermatosis type and intraepithelial neutrophilic type) that to our knowledge are the first Scandinavian patients with this disease. Initially, both patients were misdiagnosed as subcorne...

We describe the case of a 67-year-old woman affected by pemphigus vulgaris with a dry whitish scaly lesion in the upper lip. Clinically, this lesion resembled an actinic keratosis. Although histological examination revealed a focal acantholysis, the finding of a moderate-to-severe dysplastic epithelium was consistent with the diagnosis of acantholytic actinic keratosis with moderate/severe dysp...

Darier's disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules primarily affecting seborrheic areas on the head, neck, thorax, and less frequently the oral mucosa. When oral manifestations are p...

Apoptosis plays a role in pemphigus IgG-dependent acantholysis; theoretically, the blockade of the caspase pathway could prevent the blistering that is caused by pemphigus autoantibodies. Using this strategy, we attempted to block the pathogenic effect of pemphigus IgG in Balb/c mice by using the caspase inhibitor Ac-DEVD-CMK. This inhibitor was administrated before the injection of pemphigus I...

One of the most amazing lexical insights of Hrozny ! in his Die Sprache der Hethiter may be seen in his Semitic etymology of a Hittite musical term that he discovered. While discussing the use of the logogram LÚNAR “singer, musician”, he established that in KBo I 52 obv. 15-16 after the ideogram a noun that we now read as LÚki-nir-tal-la-aÍ1 follows, which he characterized as “synonym oder zumi...