Halogenated acetates alone and in combination with dextrose and formaldehyde will protect against heat denaturation of plasma proteins even when plasma is heated for 10 hr. at 60#{176}. Application of this principle would afford reclamation of plasmafrom outdated bloodbank blood. Changes in protein patterns were observedby paper electrophoresis.Other measurementsof denaturation were pH, absorba...

One-pot synthesis of substituted pyrroles by a cascade reaction of azides with Morita-Baylis-Hillman acetates of acetylenic aldehydes is described and the reaction is efficiently mediated by triphenyl phosphine at room temperature. Sodium azide is successfully used to provide N-unsubstituted pyrroles, while alkyl azides afforded the corresponding N-alkylated pyrroles through a sequence of allyl...

The lipase kinetic resolution (KR) of aryloxy-propan-2-yl acetates, via hydrolysis, produced enantiomerically pure/enantioenriched mexiletine intermediates and analogs. Racemic acetates rac-1-(2,6-dimethylphenoxy)propan-2-yl acetate (rac-5a), rac-1-(2,4-dimethylphenoxy)propan-2-yl (rac-5b), rac-1-(o-tolyloxy)propan-2-yl (rac-5c) rac-1-(naphthalen-1-yloxy)propan-2-yl (rac-5d) were used as substr...

Adenosine analogs in which the sugar unit was replaced by a 1,4-dioxane sugar equivalent, were prepared by coupling the 1,4-dioxane sugar analog as its anomeric acetates, with N6-benzoyl protected adenine. The 1,4-dioxane system was obtained in an enantioselective synthesis from (R,R)-dimethyl tartrate. Using standard phosphorimidite methodology, the adenine analog was further reacted with a 1,...

Approximately 100 billion aluminum cans are produced annually, mainly for the beverage industry. Early technologies for decorating the cans often used solvent-based coatings containing solvents at concentrations of -70% to 75% by volume (Randall 1992). The solvent composition was typically a mixture of aliphatic hydrocarbons, aromatics, ethers, cellosolves, and acetates. Unfortunately, this met...

Arylalkynes can be converted into α-diketones with the use of a copper catalyst, and also be transformed into vinyl acetates under metal-free conditions, both in the presence of PhI(OAc)2 as an oxidant at room temperature. A series of substituted α-diketones were prepared in moderate to good yields. A variety of vinyl halides could be regio- and stereo-selectively synthesized under mild conditi...

We have prepared supported gold, palladium and gold–palladium bimetallic catalysts by the physical mixing of the acetate salts of the metals followed by a simple heat treatment. The use of the acetates as the metal precursor eliminates chloride from the catalyst preparation step. Extensive characterisation shows the formation of bimetallic alloy particles. These catalysts are extremely active f...

N-Alkyl perfluorooctane sulfonamides have been widely used as surfactants on fabrics and papers, fire retardants, and anticorrosion agents, among many other commercial applications. The broad use, global distribution, and environmental persistence of these compounds has generated considerable interest regarding potentially toxic effects. We have previously reported that perfluorooctanesulfonami...

During our study of the hydrolysis of steroid acetates by bovine blood albumin, it was observed that, if cortisone acetate was transferred to the incubation medium with acetone, the ultraviolet absorption at 240 rnp was completely lost in 24 hours. A survey of the literature showed that the conjugated system might have been destroyed by enzymatic reduction of the double bond or the 3-keto group...

Although reperfusion of an ischemic organ is essential to prevent irreversible tissue damage, it may amplify tissue injury. This study investigates the role of endogenous testosterone in myocardial ischemia reperfusion and apoptosis in male rats. Material and method. Twenty four male rats were randomized into 4 equal groups: Group (1), sham group, rats underwent the same anesthetic and surgical...