AIMS To determine whether myelodysplastic syndromes (MDS) are associated with sea blue histiocytosis in the bone marrow. METHODS A retrospective review of bone marrow aspirates from 35 patients presenting consecutively with MDS and from 20 patients with each of the following: normal marrow appearance (routine staging for non-Hodgkin's lymphoma), polycythaemia rubra vera, immune thrombocytopen...

The 2,3-dihydroxybiphenyl 1,2-dioxygenase (2,3-DBPD) of Pseudomonas putida OU83 was constitutively expressed and purified to apparent homogeneity. The apparent molecular mass of the native enzyme was 256 kDa, and the subunit molecular mass was 32 kDa. The data suggested that 2,3-DBPD was an octamer of identical subunits. The nucleotide sequence of a DNA fragment containing the bphC region was d...

INTRODUCTION ............................................................ 291 QUANTITATIVE COMPARISONS OF VIRULENCE: PROPERTIES OF VIRULENT AND ATTENUATED STRAINS ................ .......... 292 ENTRY OF THE HOST: SURVIVAL ON AND PENETRATION OF MUCOUS MEMBRANES ............. ................................. 292 REPLICATION IN VIVO .................................................... 294 COUNTE...

Hen ovalbumin (OVA) is known to exist as a singly N-glycosylated form with a glycan chain on Asn-292 in egg white. Previous studies showed that di-N-glycosylated form of OVA [Di-OVA; CHO-Asn-292/CHO-Asn-311 (CHO, N-glycan chain)], which has two N-glycan chains on Asn-292 and Asn-311, was expressed only transiently in hen oviduct. Di-OVA was not found in egg white, suggesting that this form cann...

Unmordanted haematein in aqueous solution varies in colour from yellowish orange at pH 3 to bluish magenta at pH 9. In the presence of aluminium sulphate, the colour of solutions of haematein at any particular pH depends on the number of aluminium atoms to each molecule of haematein. At pH 4-6 the colour varies from yellowish orange through dull red to rose as the number of aluminium atoms to e...

Abstract We previously developed TANTIGEN, a comprehensive online database cataloging more than 1000 T cell epitopes and HLA ligands from 292 tumor antigens. In TANTIGEN 2.0, we significantly expanded coverage in both immune response targets (T ligands) It catalogs 4,296 antigen variants 403 unique antigens 1500 ligands. also included neoantigens, class of generated through mutations resulting ...