Background: Protective effect of Emblica against radiation and cadmium induced biochemical changes in mouse kidney has been studied. Materials and Methods: Adult male mice were divided into seven groups: I (shamirradiated), II (cadmium chloride), III (irradiated with 2 Gy gamma rays), IV (radiation and cadmium chloride), V (Cadmium chloride and Emblica), VI (radiation and Emblica), VII...

The study aimed to examine the effect of extracted and standard ursolic acid in addition hyperinsulinemia compared vitamin B complex on liver kidney function alloxan-induced diabetic male rabbits. functions were determined analyzed by one–way a NOVA at variance software P-Value 0.05. result showed significant decrease aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP), ...

BACKGROUND Macrophages that uptake modified lipoproteins are activated and may initially behave as endotoxin-stimulated macrophages. This study was undertaken in order to determine whether signal transduction pathways controlling endotoxin-mediated activation may also influence the lipoprotein-mediated activation of macrophages. MATERIALS AND METHODS Rat peritoneal macrophages were incubated ...

The abundant surface glycolipid, lipophosphoglycan (LPG), of Leishmania promastigotes is composed of phosphosaccharide repeating units linked via a phosphosaccharide core to a conserved lyso alkylphosphatidylinositol membrane anchor. It is shown in this paper that monoclonal antibodies (mAbs) directed against LPG also react with an acid phosphatase secreted by L. mexicana promastigotes. Acid ph...

The cholic acid CoA ligase activity of rat liver was quantitatively inactivated by proteolysis with pronase, chymotrypsin, subtilisin, or proteinase K in intact microsomal vesicles. Under the conditions employed, less than 14% of the lumenal mannose-6-phosphate phosphatase activity was lost, and the mannose-6-phosphate phosphatase activity remained highly latent. After microsomal integrity was ...

A simple and sensitive colorimetric assay for protein phosphatase activity based on the determination of released Pi by an improved malachite green procedure (A. A. Baykov, O. A. Evtushenko, and S.M. Avaeva, 1988, Anal. Biochem. 171, 266-270) is described. Proteins must be removed or stabilized prior to Pi determination with 0.25 N sulfuric acid or 3% (w/w) perchloric acid. Alternatively, to av...