Realisation of a device intended for the manipulation and detection of bead-tagged DNA and other bio-molecules is presented. Acoustic radiation forces are used to manipulate polystyrene micro-beads into an optical evanescent field generated by a laser pumped ion-exchanged waveguide. The evanescent field only excites fluorophores brought within approximately 100 nm of the waveguide, allowing the...

Surface acoustic wave (SAW) sensors are currently being investigated in a wide range in fields including physical, chemical and bio-sensing. The basic principle in a SAW sensor is the detection of changes in the propagation characteristics of the surface acoustic waves which are caused by perturbations on the active surface of the device. The most common situation is measuring the change in pro...

For adults, ownership is nonobvious: (a) determining ownership depends more on an object's history than on perceptual cues, and (b) ownership confers special value on an object ("endowment effect"). This study examined these concepts in preschoolers (2.0-4.4) and adults (n=112). Participants saw toy sets in which 1 toy was designated as the participant's and 1 as the researcher's. Toys were the...

The present research investigates whether spontaneous trait inferences occur under conditions characteristic of social media and networking sites: nonextreme, ostensibly self-generated content, simultaneous presentation of multiple cues, and self-paced browsing. We used an established measure of trait inferences (false recognition paradigm) and a direct assessment of impressions. Without being ...

During adolescence, concerns about peer rejection and acceptance become increasingly common. Adolescents regularly experience peer rejection firsthand and witness these behaviors among their peers. In the current study, neuroimaging techniques were employed to conduct a preliminary investigation of the affective and cognitive processes involved in witnessing peer acceptance and rejection - spec...

Language comprehension requires rapid and flexible access to information stored in long-term memory, likely influenced by activation of rich world knowledge and by brain systems that support the processing of sensorimotor content. We hypothesized that while literal language about biological motion might rely on neurocognitive representations of biological motion specific to the details of the a...

Humans have the remarkable capacity to learn words from a single instance. The goal of this study was to examine the impact of initial learning context on the understanding of novel word usage using event-related brain potentials. Participants saw known and unknown words in strongly or weakly constraining sentence contexts. After each sentence context, word usage knowledge was assessed via plau...

Amblyopes exhibit a global motion anomaly that implicates processing beyond the local motion analysis of V1 possibly involving areas MT and MST in the extra-striate cortex. Here, we sought to further investigate this deficit by measuring the perception of moving plaid stimuli by amblyopic observers, since there is good physiological evidence that the motion of such stimuli is determined by proc...

The intuition of chance and probability develops at very early ages.1 However, a formal, precise definition of the probability is elusive. If the experiment can be repeated potentially infinitely many times, then the probability of an event can be defined through relative frequencies. For instance, if we rolled a die repeatedly, we could construct a frequency distribution table showing how many...

Seventeenth and eighteenth century America saw relatively egalitarian and stable aggregate wealth concentration. During the first half of the nineteenth century, in contrast, there was a marked rise in wealth concentration. The period from the Civil War to the Great Depression was also one of stability in wealth concentration, but it was characterized by substantially greater inequality than ha...