Subcortical aphasia develops as a result of damage to subcortical brain areas without loss cortical functions. Although earlier voxel-based lesion-symptom mapping (VLSM) studies have shown possible neural correlates for aphasia, it remains be clarified which regions are associated with aphasia. The aim this study was investigate the substrates in patients stroke using VLSM and atlas-based analy...

Background and Aims Previous studies have shown that age of acquisition affects language production in persons with aphasia (PWA), specifically, earlier-acquired words are better preserved compared to later-learned ones (for review, see Brysbaert & Ellis, 2016). Also, it has been argued naming objects lower name agreement requires inhibition alternative names (Alario et al., 2004), therefore pu...

Patients with Wernicke's or expressive aphasia are able to produce fluent speech, however, this speech may be complete gibberish sounds and totally incomprehensible, or even when comprehensible to a degree is often laced with severe errors and abnormalities such as verbal and phonemic paraphasias and neologisms. Furthermore, patient's with Wernicke's aphasia have poor to no understanding of spe...

OBJECTIVE Stroke patients with aphasia have a high long-term morbidity. Intravenous rt-PA (iv) thrombolysis is given more deliberately to these patients. Early outcome data is lacking. Aim of this study was to determine early benefit from rt-PA in patients with aphasia. METHODS Data of stroke patients treated by iv thrombolysis was scrutinized for the presence of aphasia defined as ≥1 point f...

BACKGROUND Constraint-induced aphasia therapy (CIAT) has been widely used in post-stroke aphasia rehabilitation. An increasing number of clinical controlled trials have investigated the efficacy of the CIAT for the post-stroke aphasia. PURPOSE To systematically review the randomized controlled trials (RCTs) concerning the effect of the CIAT in post-stroke patients with aphasia, and to identif...

UNLABELLED The relation between other aspects of cognition and language status of individuals with aphasia is not well-established, although there is some evidence that integrity of non-linguistic skills of attention, memory, executive function and visuospatial skills can not be predicted on the basis of aphasia severity. At the same time, there is a growing realization among rehabilitation spe...

BACKGROUND A cardioembolic source, usually atrial fibrillation (AF), is detected in 14-30% of strokes. If AF is found, anticoagulation therapy provides a substantial decrease of the risk of recurrent cerebrovascular ischemic events. AF is often paroxysmal, and extensive diagnostic procedures may be necessary to detect it in patients. Considering cost-effectiveness and patient burden, however, n...

BACKGROUND AND PURPOSE In a geographically defined population, we assessed incidence and determinants of aphasia attributable to first-ever ischemic stroke (FEIS). METHODS A 1-year prospective, population-based study among the permanent residents of the canton Basle City, Switzerland, was performed using multiple overlapping sources of information. RESULTS Among 188,015 inhabitants, 269 pat...

Positive outcomes from intensive therapy for individuals with aphasia have been reported in the literature. Little is known about the characteristics of individuals who attend intensive comprehensive aphasia programs (ICAPs) and what factors may predict who makes clinically significant changes when attending such programs. Demographic data on participants from 6 ICAPs showed that individuals wh...

Background: People with aphasia have been engaging research in a variety of ways. There are few descriptions how they involved participatory methodologies and even fewer reports describe their perspective on participating as co-researchers.Aims: To explore the experiences reflections two people aphasia, BG MG, being studies co-researchers – Conversation Partner Programme Evaluation Project Frie...