OBJECTIVE To quantify the effects of varying opioid prescribing patterns after surgery on dependence, overdose, or abuse in an opioid naive population. DESIGN Retrospective cohort study. SETTING Surgical claims from a linked medical and pharmacy administrative database of 37 651 619 commercially insured patients between 2008 and 2016. PARTICIPANTS 1 015 116 opioid naive patients undergoin...

BACKGROUND AND AIMS Since its market release, gabapentin has been presumed to have no abuse potential and subsequently has been prescribed widely off-label, despite increasing reports of gabapentin misuse. This review estimates and describes the prevalence and effects of, motivations behind and risk factors for gabapentin misuse, abuse and diversion. METHODS Databases were searched for peer-r...

Many governmental and non-governmental organizations have distributed insecticide-treated nets (ITNs) to malaria endemic areas, which contributed to the reduction of malaria deaths. However, some people in malaria endemic areas used ITNs for alternative purposes such as fishery and agriculture. It is unclear why people threatened by malaria misuse ITNs. Here we develop a N-player mosquito net g...

objective: substance misuse is a major public health threat in iran. the total number of addicts in iran is estimated to be between 700,000 and 4,000,000. a few limited household studies on the prevalence of substance misuse have been performed in iran. method: the residents of the sixth district of the municipality of tehran who were over the age of 15 were selected as the study population. th...