OBJECTIVE To guide immunization policy, we determined the public health benefit of introducing Haemophilus influenzae type b (Hib) vaccine in Uganda and estimated the vaccine effectiveness. METHODS Surveillance data for acute bacterial meningitis among children aged 0-59 months were reviewed from three hospital sentinel sites, for July 2001 to June 2007, to determine the incidence of Hib meni...

Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, which are known as the meninges. This infection may be caused by Streptococcus pneumonia bacteria. In this study, we presented the case of a female newborn with meningitis secondary to Streptococcus pneumonia. Her birth weight and height were normal. After 24 hours of birth, the neonate was diagn...

results out of 2229 suspected meningitis cases, 255 (11.4%) were detected as positive culture. most of the isolates were gram-positive cocci, which 116 (45.5%) were staphylococcus epidermidis, and 20 (7.8%) identified as streptococcus spp. among gram-negative isolates, escherichia coli and acinetobacter spp., each with 19 isolates (5.9%), were predominant. overall, the most effective antibiotic...

AIMS Brighton Collaboration (BC) case definitions are independent from presumed causes or triggers, hence should be applicable in routine clinical settings. SCOPE 255 cases with discharge diagnoses of aseptic meningitis (ASM; n=164), encephalitis (ENC; n=48), myelitis (MYE; n=8), ADEM (n=10), or bacterial meningitis (BM; n=59; control group) were tested against the BC case definitions ASM, EN...

Acute bacterial meningitis is a life-threatening neurological emergency. Its estimated annual incidence is 2–5 per 100 000 people in the Western world and a figure that may be 10 times as high in the less developed countries. Bacterial meningitis is one of top 10 causes of infection-related death worldwide and 30– 50% of its survivors have permanent neurological sequelae. Conditions that predis...

The principles of antimicrobial therapy for acute bacterial meningitis include use of agents that penetrate well into cerebrospinal fluid and attain appropriate cerebrospinal fluid concentrations, are active in purulent cerebrospinal fluid, and are bactericidal against the infecting pathogen. Recommendations for treatment of bacterial meningitis have undergone significant evolution in recent ye...

most frequent etiological agent, however only a few studies have focused on the clinical and pathological features of the illness in adults.b , 7-10 Knowledge of the entire clinical spectrum of complications and their prompt detection are a prerequisite for the improved management of the disease. Therefore, the aim of this study was to obtain data on predisposing factors, causative organisms an...

BACKGROUND Bacterial meningitis is still considered as one of the most dangerous infectious diseases, which causes numerous complications and high mortality if not diagnosed and treated timely. OBJECTIVES This study was performed to determine antimicrobial resistance patterns of bacterial pathogens isolated from acute bacterial meningitis at Tabriz Children Educational-Health Care Center in I...

To precis the aetiologies of children meningitis and the susceptibility to antibiotics of bacteria responsible for meningitis in Bangui, we conducted a prospective study between October 2004 and September 2005, at the 'Complexe Pédiatrique de Bangui', Central African Republic (CAR). Children from 1 day to 16 years with suspected meningitis and who underwent a lumbar puncture were enrolled. Gram...

OBJECTIVE To describe bacteriological profile, morbidity and mortality of acute bacterial meningitis (ABM) in children and to compare these parameters before and after the introduction of Pneumococcal vaccine in Pakistan National Immunization Program. METHODS The present descriptive study was conducted at the Department of Paediatric Medicine of The Children's Hospital Lahore from January 201...