Cutaneous Leishmaniasis may present with clinical presentation such as zosteriform, sporotrichoid and erysipeloid. The eczema variant has rarely been reported. We report a 27- year- old patient with atypical cutaneous leishmaniasis resembling eczema on the hand of a man in Yazd province in the central of Iran.

BACKGROUND Cutaneous leishmaniasis is a neglected parasitic disease, which imposes massive human distress and financial costs to the endemic countries. Better understanding of host immune response to the parasite leads to helpful strategies for disease control. Interleukin (IL)-10 and transforming growth factor (TGF)-β are important immune regulatory cytokines, which appear to develop non-heali...

BACKGROUND Cutaneous leishmaniasis is a chronic, infectious disease caused by protozoa of the genus leishmania. The incidence of this disease is high in Brazil, with 19,746 new cases having been detected in 2008. The presence of amastigotes in the cytoplasm of histiocytes constitutes diagnosis of the disease; however, their presence is rarely found in late lesions, making histological diagnosis...

background: cutaneous leishmaniasis (cl) is a major health problem in many parts of iran, although diagnosis of cl especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. diag-nosis of cl in non-endemic area is not as simple as in endemic foci. in this study, the status and the proportions of cl induced by leishmania major and l. tropica among cl...

conclusions according to the current study results, it may be concluded that ethanol extract of p. harmala is efficient in the treatment of cutaneous leishmaniasis, and the efficiency is comparable with that of glucantime. results the results showed that ethanol extract of p. harmala had good therapeutic efficacy in treatment of lesions in mice (p < 0.05), and the efficacy was significant in th...

results fifty four of 84 (64.2%) slides obtained from patients had positive results microscopically, while 79/84 (94%) of slides had positive results by fta card-nested-pcr. pcr and microscopy showed a sensitivity of 96.4% and 64.2% and specificity of 100% and 100%, respectively. interestingly, leishmania major as causative agent of zoonotic cl was identified in 100% and 90.7% of cl cases from ...

b a ckground: the objective of this study was to assess the epidemiological characteristics of a new emerging focus of cutaneous leishmaniasis (cl) in southern villages of bam district, southeastern iran, 2010. m e t hods: a house-to- house census survey of 5544 individuals were interviewed and physically examined for the presence of active lesions or scars. diagnosis was confirmed by direct sm...

the world health organization (who) has supported and recommended study and research on the various aspects of leishmaniasis which is one of the six major tropical region diseases. cutaneous leishmaniasis is considered as a common parasitic disease in iran. considering the fact that few studies have been conducted about some centers of disease such as khorram-shahr and the information about the...

An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana. In an attempt to pinpoint alterations in the signaling pathways responsible for the NK-cell dysfunction in patients with DCL, this study aimed at identifying differences in the NK-cell response towa...