Bg ARTHUR F. GOLDBERG AND HELEN WENDLER DEANE T HIS STUDY was made to characterize intracellular crystals found in unusual lympho-plasmocytoid cells, which have been described elsewhere’ and for convenience will be termed crystal cells. For comparison, an examination was made of the related inclusions in plasmocytes ( Russell bodies ) , and also of primary, secondary, and senile cardiac amyloid...

This occurred whether Tilorone was administered p.o. or i.p. When administered 24 hr after L1210 cells, an adjuvant effect of Tilorone upon CMI was not demonstrable unless glass-adherent spleen cells were removed before in vitro assay. In groups given Tilorone or L1210 alone, CMI was unchanged after removal of adherent cells. Release of lymphocyte-activating factor by the spleen was unaffected ...

Castleman’s disease is a rare lympho proliferative disorder with unclear pathogenesis. It is found in two forms, localized (uni-centric) and multi-centric. Histologically there are two forms; hyaline vascular and plasma cell type. The disease is definitely diagnosed by histological examination after biopsy. Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Gallium 67 scintigraphy can ...

Five year survival rates for early stage localized disease are over80% but this drops to 40% where disease has spread to the neck and to below 20% for distant metastatic disease. Early intervention is appropriate. Factors affecting the prognosis of oral cancer are based on tumor, node and metastasis (TNM) classification which stages the patient according to the size of the primary tumor and the...

interest by providing: a) a brief summary of accomplishmethods of donor-recipient matching were not available, ments which have already been possible with the admitexcept for the assurance of compatible blood types. The tedly imperfect immunosuppressive regimens now in use; results, therefore, were obtained with relatively random b) a critique of the drugs or drug combinations currently donor s...

Netherton Syndrome (NS) is a very rare genetic skin disease resulting from defects in the SPINK5 gene (encoding the protease inhibitor lympho-epithelial Kazal type inhibitor 1, LEKTI1). In this report, we provide a detailed clinical description of a Polish patient with two SPINK5 mutations, the novel c.1816_1820+21delinsCT and possibly recurrent c.1431-12G>A. A detailed pathogenesis of Netherto...

The immunomodulating properties of antimicrobial drugs may have important implications for clinical practice, particularly for those patients whose immune system has been compromised. In this study, we assessed the influence of different treatments with a beta-lactam antibiotic (imipenem/cilastatin) on several acquired immune responses of BALB/c mice; splenocyte responses to specific mitogens a...

Hairy cell leukemia is a relatively rare but distinct B-cell lympho-proliferative disorder of the blood, bone marrow, and spleen that accounts for only 2% of all adult leukemia cases. The median age at presentation is 50-55 years, with a 4:1 male to female predominance. Although considered uncommon, a number of unusual clinical presentations have been noted in the literature, including the pres...

Medullary carcinomas both typical (MBC) and atypical (AMBC) are rare breast tumors that account for <5% of invasive breast carcinomas [1]. The diagnosis of medullary carcinoma is usually defined by histologic diagnostic criteria proposed by Ridolfi et al. [2]. These histopathological features include: syncytial growth pattern (>75%), absence of glandular structures, diffuse lympho-plasmacytic i...

Nghiên cứu mô tả cắt ngang trên 20 bệnh nhân từ 2,5 tháng đến 12,5 tuổi được chẩn đoán nhiễm HIV-1 mới tại Bệnh viện Nhi Trung ương năm 2014 - 2017. Kết quả cho thấy số lượng và tỷ lệ % tế bào lympho TCD4 giảm, chỉ CD4/CD8 giảm. Các dưới nhóm của như Th1, Th2, Th17 giảm hơn so với bình thường, riêng Treg có không thay đổi. Số TCD8 hoạt hóa đều tăng. các (Th1, Th17, Treg), liên quan nghịch phát ...