A monoclonal antibody designated PI153/3, which reacts with neuroblastoma and fetal brain, is shown to identify also a cell surface determinant shared by pre-B and mature B cells and their corresponding leukemias including chronic lymphocytic leukemia, non-Hodgkin's lymphoma, B acute lymphoblastic leukemia, and hairy cell leukemia, but not plasmacytoma. Almost all non-T, non-B acute "lymphoid" ...

BACKGROUND Previous studies have shown increased familial risk for chronic lymphocytic leukemia. In the most comprehensive study to date, we evaluated risk of chronic lymphocytic leukemia and lymphoproliferative disorders among first-degree relatives of chronic lymphocytic leukemia cases compared to first-degree relatives of controls. DESIGN AND METHODS Population-based registry data from Swe...

Spontaneous remission or regression of cancer is defined as partial or complete disappearance of malignant disease temporarily or permanently in the absence of any specific treatment. The condition is named spontaneous regression for solid tumors and spontaneous remission (SR) for leukemia [1]. Spontaneous remission has been reported in different hematological malignancies. It has been observed...