نتایج جستجو برای: adamantane drug resistance
تعداد نتایج: 909020 فیلتر نتایج به سال:
A novel Schiff base compound, C(20)H(27)NO(2), was obtained by a condensation of rimantadine and 2-hy-droxy-4-meth-oxy-benzaldehyde. An intra-molecular O-H⋯N hydrogen bond supports the phenol-imine tautomeric form. The adamantane and imino-methyl-4-meth-oxy-phenol units are arranged in a folded conformation [C-N-C-C torsion angle = 110.9 (3)°]. In the crystal, highly hydro-phobic adamantane moi...
Most small-molecule inhibitors of voltage-gated ion channels display poor subtype specificity because they bind to highly conserved residues located in the channel's central cavity. Using a combined approach of scanning mutagenesis, electrophysiology, chemical ligand modification, chemical cross-linking, MS/MS-analyses and molecular modelling, we provide evidence for the binding site for adaman...
The title mol-ecule, C(34)H(28)I(4)·4C(6)H(6), has crystallographic symmetry and crystallizes with four symmetry-related benzene solvent mol-ecules. The phenyl group is eclipsed with one of the adamantane C-C bonds. The tetra-phenyl-adamantane units and the benzene solvent mol-ecules are connected by weak inter-molecular phen-yl-benzene C-H⋯π and benzene-benzene C-H⋯π inter-actions. In the crys...
background: listeria monocytogenes is one of the most important food-borne bacteria causing septicemia, meningitis and encephalitis in humans. the objective of this study was to evaluate the occurrence and antibiotic resistance of the bacterium in retail minced beef in ahvaz, south-west of iran. methods: in this survey, 150 samples of minced beef were randomly obtained from retail butcheries in...
abstract background and objective: enterococci are relatively nonvirulent bacteria that rarely cause disease. antimicrobial treatment of enterococci is often challenging due to their antibiotic resistance. this study aimed to investigate the antibacterial activity of aqueous extract of garlic against enterococcal isolates. methods: in this descriptive study, 120 enterococcus isolates ...
this study was planned to determine hiv seroprevalence among pulmonary tuberculosis patients, to characterize the isolated mycobacteria into typical and atypical strains and to evaluate the drug resistant pattern of mycobacterial isolates. the study aims to correlate multidrug resistance (mdr) and hiv seropositivity status in pulmonary tuberculosis patients. during the year 1994-1997, 750 pulmo...
conclusions detection and surveillance of the significant sites of mutations in hbv is crucial for clinicians to decide on the choice of antiviral treatment and further management of hepatitis b carriers. objectives this study was carried out to detect mutations in p gene of hepatitis b virus isolated from malaysian hbv carriers. materials and methods a total of 58 sera samples were analyzed by...
background and aims: genotyping assay has been accepted as a guidance in the therapeutic management of human immunodeficiency virus 1 (hiv-1). but, it is not commonly used in our country due to its high running cost. the aim of this study is evaluate an in-house genotyping resistance test (grt) for hiv-1. methods: hiv-1 rna of 20 samples were extracted from plasma and rt nested- pcr was perform...
objective(s):the colorectal cancer stem cells (cscs) with the cd133+ phenotype are a rare fraction of cancer cells with the ability of self-renewal, unlimited proliferation and resistance to treatment. quercetin has anticancer effects with the advantage of exhibiting low side effects. therefore, we evaluated the anticancer effects of quercetin and doxorubicin (dox) in ht29 cancer cells and its ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید