نتایج جستجو برای: adenomatous polyp

تعداد نتایج: 15992  

Journal: :Gut Pathogens 2021

Abstract Background Colorectal adenomatous polyps (CAPs) are considered precancerous lesions of colorectal cancer (CRC). The gut microbiota participates in the process digestion and, process, produces metabolites, mainly short-chain fatty acids (SCFAs), secondary bile and conjugated linoleic acid (CLA). This study aimed to investigate constituents metabolites faeces CAP patients identify or tha...

2014
Hassan Ashktorab Mansour Paydar Shahla Yazdi Hassan Hassanzadeh Namin Andrew Sanderson Rehana Begum Mohammad Semati Firoozeh Etaati Edward Lee Hassan Brim Anteneh Zenebe Gail Nunlee-Bland Adeyinka O. Laiyemo Mehdi Nouraie

OBJECTIVES Obesity is associated with the activation of the molecular pathways that increase the risk of colorectal cancer. Increasing body mass index may accelerate the development of adenomatous polyps, the antecedent lesion of colorectal cancer. The aim of this study was to assess the BMI effect on the risk of colonic polyp and adenoma in African-American. METHODS The records of 923 patien...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004
Frank A Sinicrope Elizabeth Half Jeffrey S Morris Patrick M Lynch Jason D Morrow Bernard Levin Ernest T Hawk Deborah S Cohen Gregory D Ayers L Clifton Stephens

BACKGROUND Celecoxib was shown to regress colorectal adenomas in familial adenomatous polyposis (FAP) patients relative to placebo. To address the mechanism of polyp regression, we determined whether celecoxib can modulate cell proliferation, apoptosis, and prostaglandin E(2) (PGE(2)) levels in colorectal epithelia from FAP trial participants and whether such alterations correlate with observed...

Journal: :Polish journal of pathology : official journal of the Polish Society of Pathologists 2013
Dariusz Waniczek Mirosław Śnietura Joanna Młynarczyk-Liszka Wojciech Pigłowski Agnieszka Kopeć Dariusz Lange Marek Rudzki Jerzy Arendt

The aim of the study was to determine expression of the PTEN suppressor gene in colorectal adenocarcinoma and its precancerous lesions (adenomatous polyps) in correlation with common clinical and histopathological features. Forty-four patients with adenomatous polyps and 32 with primary adenocarcinoma of the colon or rectum were enrolled in the study. They underwent endoscopic removal of polyps...

2015
Rina Zuniga Josef Bautista Katherine Sapra Keith Westerfield Susan Williams Alexander M. Sy

Aim. The aim of the paper is to determine association between H. pylori and colonic adenomatous polyps and to explore whether treatment or chronic PPI use can mitigate this risk. Methods. This case-control study included 943 patients who had H. pylori testing and underwent colonoscopy. Presence of polyps was the outcome of interest, whereas age, sex, race, H. pylori infection, triple therapy, a...

Journal: :Gut 1987
J S Gelister M R Lewin H E Driver F Savage M Mahmoud P J Gaffney P B Boulos

An important step in the transition from adenomatous polyp to invasive carcinoma is the degradation of the epithelial basement membrane. By the generation of plasmin, plasminogen activators may play an important role in regulating the extracellular protease activity required for this event to occur. The production of biofunctional urokinase and of tissue plasminogen activator was therefore inve...

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