PURPOSE Perioperative intravesical chemotherapy following transurethral resection of bladder tumor has been underused despite level 1 evidence supporting its performance. The primary objective of this study was to estimate the economic and humanistic consequences associated with preventable recurrences in patients initially diagnosed with nonmuscle invasive bladder cancer. MATERIALS AND METHO...

OBJECTIVES To investigate the cost-effectiveness of a telehealthcare solution in addition to usual care compared with usual care. DESIGN A 12-month cost-utility analysis conducted alongside a cluster-randomised trial. SETTING Community-based setting in the geographical area of North Denmark Region in Denmark. PARTICIPANTS 26 municipality districts define randomisation clusters with 13 dis...

BACKGROUND The response to therapeutics varies widely in patients with depression and anxiety, making selection of an optimal treatment choice challenging. IDgenetix®, a novel pharmacogenomic test, has been shown to improve outcomes by predicting the likelihood of response to different psychotherapeutic medications. OBJECTIVE The objective of this study was to estimate the cost effectiveness ...

AIM To investigate the cost-effectiveness of liraglutide as add-on to metformin vs. glimepiride or sitagliptin in patients with Type 2 diabetes uncontrolled with first-line metformin. METHODS Data were sourced from a clinical trial comparing liraglutide vs. glimepiride, both in combination with metformin, and a clinical trial comparing liraglutide vs. sitagliptin, both as add-on to metformin....

PURPOSE To evaluate the incremental effectiveness and cost-effectiveness of a staged-based, computerized smoking cessation intervention relative to standard care in an urban managed care network of primary care physicians. DESIGN Decision-analytic model based on results of a randomized clinical trial. METHODOLOGY Patient outcomes and cost estimates were derived from clinical trial data. Eff...

BACKGROUND Genomic tests may improve the stratification of patients to receive new therapies in several disease areas. However, the use of expensive targeted therapies can impact on the cost effectiveness of these tests. This study presents an economic evaluation of genomic testing in chronic lymphocytic leukaemia in the context of the UK National Health Service. METHODS Cost-effectiveness an...

No one likes to admit that money matters in health care, but it does. One tool for comparing the cost of treatments or interventions, such as chemoprevention, is the cost-effectiveness study. A cost-effectiveness study compares the incremental cost of treatment to the incremental benefit. To determine cost per life-year gained, a researcher will take the cost of the treatment—usually determined...