Adrenal necrosis has been described in golden hamsters where it occurs during the course of infection with Besnoilia jellisoni. This necrosis results directly from the active intracellular proliferation by this obligate intracellular protozoan organism. After infection, adrenal necrosis is rarely observed in hypophysectomized hamsters. In unoperated animals adrenal necrosis is suppressed to var...

BACKGROUND The endocrine adrenal gland has 3 zones comprised of the cortex and medulla. The character of multi-hormonal expression results in multiple clinical manifestations. To define the clinical characteristics of adrenal tumors in Taiwan, we reviewed 336 pathologically proven adrenal tumors at Chang Gung Memorial Hospital in Linkou. METHODS We retrospectively analyzed 258 pathologically ...

and lesions following the appearance of adrenal cortical carcinomas presents a new line of evidence for the close relationship of adrenal cortex and pituitary disfunctions in experimental animals and of these disfunctions to tumor formation and their possible inherited tendencies. In man, there are not sufficient data to say conclusively whether the adrenal cortex or anterior pituitary abnormal...

• Acute infarctoid myocardial necrosis can be produced in virgin rats by injection of the potent catecholamine, isoproterenol. We have noted that these myocardial lesions are essentially identical, both grossly and microscopically, to acute infarcts which occur spontaneously in the hearts of breeder rats with arteriosclerosis."" Rats with drug-induced myocardial necrosis show signs of shock whi...

Year 2010 marks a centennial anniversary of the description by Stella Starkel and Lesław Węgrzynowski, Polish students of the Faculty of Medicine, University of Lwów, the fetal zone of the human fetal adrenal gland. In 1911 both, Starkel and Węgrzynowski were graduated from the Faculty of Medicine of Lwow University. The paper appeared in the German Arch. Anat. Physiol. and its original title w...

Adrenal masses pose a diagnostic challenge. The differential diagnosis includes functional adrenal tumors, incidentally found adrenal masses, metastases from an unknown primary cancer, and abscesses. Infrequently, adrenal gland abscesses have been reported in disseminated nocardiosis affecting immunocompetent and immunocompromised patients. We report a case of disseminated Nocardia farcinica pn...

Adrenalectomies in dogs are being more commonly performed, however anaesthetic management of such cases can be challenging due to the multiple aetiologies of adrenal tumours and the physiological role of adrenal glands. This case report describes the anaesthetic management of a dog with clinical signs of hyperadrenocorticism that underwent unilateral adrenalectomy via laparotomy and discusses a...

Our knowledge of the functions of the normal and diseased adrenal cortex in adults is still slight and we know even less about it in newborn babies and in children. In the past few years an increasing number of methods for examining adrenal function have been described. In addition to the determination of the total amount of 17-ketosteroids (17-KS) and of 17-hydroxycorticoids (17-OH) excreted i...

Two patients had a long history of hypertension and one of them also had a nephrotic-range proteinuria secondary to focal segmental scleronephrosis which had been diagnosed by kidney biopsy. They presented with uncontrolled hypertension. Laboratory examination suggested hypersecretion of catecholamines by the left adrenal glands in both patients and primary aldosteronism in one of them. A compu...

A 54-year-old patient was found to have an aldosterone-producing microadenoma measuring 2.5 mm in diameter. Although adrenal venography by selective catheterization had failed to demonstrate the tumour, adrenal scintiscan using 131I-19-iodocholesterol accurately localized the functional tumour in the right adrenal gland; a dexamethasone-modified adrenal scintiscan revealed complete suppression ...