BACKGROUND Symptoms of attention-deficit hyperactivity disorder (ADHD) are known to persist into adulthood in the majority of cases. AIMS To determine the prevalence of methylphenidate, dexamfetamine and atomoxetine prescribing and treatment discontinuation in adolescents and young adults. METHOD A descriptive cohort study using the UK General Practice Research Database included patients ag...

BACKGROUND Since 1999, we have treated HIV-positive men with sperm washing as part of a risk-reduction programme. METHODS Retrospective analysis of the sperm-washing database from the treatment of 245 couples with 439 cycles of intrauterine insemination assessed the effects of patient factors (age, maternal FSH, rank of attempt), markers of HIV-disease [time since diagnosis, CD4 count, viral ...

PURPOSE To analyze the corneal endothelial cell density in healthy adult emmetropic subjects. METHODS We analyzed the corneal endothelial cell density of a group made up of 225 emmetropic subjects (n=225). As age-matched control groups we analyzed two other groups, one made up of myopic subjects (n=209) and the other made up of hyperopic subjects (n=203). We recorded the mean of three consecu...

BACKGROUND High cholesterol levels are associated with increased risk of coronary heart disease and stroke. Understanding the distribution of serum cholesterol levels in each country is valuable index for use in public health planning. This study aimed to construct nomograms of total cholesterol (TC) levels and establish the cut-points specific to Iranian population. METHODS Data on serum TC ...

BACKGROUND Population-based studies have revealed declining acute ischemic stroke (AIS) hospitalization rates in the United States, but no study has assessed recent temporal trends in race/ethnic-, age-, and sex-specific AIS hospitalization rates. METHODS AND RESULTS Temporal trends in hospitalization for AIS from 2000 to 2010 were assessed among adults ≥25 years using the Nationwide Inpatien...

White blood cell counts (WBC) were measured in 7,739 healthy black individuals, ages one through 84 years, to determine normal values for different age and sex groups. The mean WBC was highest in children one to two years of age, regardless of sex. The mean count decreased progressively in both males and females during preschool years, reaching a nadir in females six to 10 years of age and in m...

OBJECTIVE To examine the long-term effects of the Seattle Social Development Project intervention in promoting positive adult functioning and preventing mental health problems, crime, and substance use (including tobacco, alcohol, and other drugs) at 21 years of age. DESIGN This nonrandomized controlled trial followed up participants to 21 years of age, 9 years after the intervention ended. W...