Early development drug formulation is exacerbated by increasingly poor bioavailability of potential candidates. Prevention of attrition due to formulation problems necessitates physicochemical analysis and formulation studies at a very early stage during development, where the availability of a new substance is limited to small quantities, thus impeding extensive experiments. Miniaturization of...

Most estimates of sea spray aerosol source functions have used indirect means to infer the rate of production as a function of wind speed. Only recently has the technology become available to make high frequency measurements of aerosol spectra suitable for direct eddy correlation determination of the sea spray particle flux. This was accomplished in this study by combining a newly developed fas...

A 46-year-old man who had worked as a bumper spray painter in an automobile body shop for 15 years developed lung cancer. The patient was a nonsmoker with no family history of lung cancer. To determine whether the cancer was related to his work environment, we assessed the level of exposure to carcinogens during spray painting, sanding, and heat treatment. The results showed that spray painting...

Suitability of the Sauter mean diameter and the surface-area mean diameter for representing the ignition and combustor behavior of polydisperse sprays is examined. Initial size distributions considered are the Nukiyama-Tanasawa distribution and a bidisperse spray. Two physical situations are analyzed. In the first, the ignition characteristics of a polydisperse spray in the viscinity of a hot w...

A distributed dynamic model was built using gPROMS 2.3.7 language for an integrated Process including a cogeneration system, a plate heat exchangers set and a salt recrystallization process. It was analyzed the effect of a simulated spray system model on the integrated process, by comparing the global performance of the system with and without sprays. Due to air drift issues, quasi-random time ...

Photoluminescence of highly structured ZnO layers comprising well-shaped hexagonal rods is presented. The ZnO rods (length 500-1,000 nm, diameter 100-300 nm) were grown in air onto a preheated soda-lime glass (SGL) or ITO/SGL substrate by low-cost chemical spray pyrolysis method using zinc chloride precursor solutions and growth temperatures in the range of 450-550°C. We report the effect of th...

Two different spray application methods were compared in three vine varieties and different crop stages. A conventional spray application with a constant volume rate per unit ground area (l•ha1) was compared with a variable rate application method designed to compensate electronically measured variations of canopy dimensions. An air-blast sprayer with individual multi-nozzle spouts was fitted u...

Single-crystal semiconductors have been at the forefront of scientific interest for more than 70 years, serving as the backbone of electronic devices. Inorganic single crystals are typically grown from a melt using time-consuming and energy-intensive processes. Organic semiconductor single crystals, however, can be grown using solution-based methods at room temperature in air, opening up the po...

This work evaluates the suitability of iron aluminide coatings for use in high temperature fossil fuel combustion environments, such as boiler applications. The coatings are applied using High Velocity Oxy-Fuel (HVOF) thermal spray techniques. Bulk Fe3Al coatings are known to exhibit excellent oxidation and sulfidation resistance at high temperatures, however, the behavior of HVOF-deposited Fe3...