30 Vasovagal syncope is a disorder that has been known for years since its clinical characteristics were masterfully described by Sir Thomas Lewis at the beginning of the 20th century.1 Traditionally, the criteria used to establish the diagnosis of a vasovagal origin in patients with syncopal episodes was based only on the presence of triggering circumstances and typical prodromic symptoms. In ...

OBSTRUCTION OF THE UPPER AIRWAY IN SLEEP APNEA SYNDROME (OSAS) IS ASSOCIATED WITH DIMINISHED NEUROMUSCULAR ACTIVITY OF THE DILATING MUSCLES1 THAT STIFFEN THE PHARYNGEAL AIRWAY DURING INSPIRATION.2 The ineffective muscle response to hypercapnia, hypoxia, or negative pressure has been proposed as a possible predisposing factor for OSAS.3 Moreover, breathing through a narrowed airway generates a g...

involved in the transmission of leishmaniasis. The association of sandflies and bacteria is still an incipient field although there are evidences of interaction amongst the sandfly host-Leishmania parasite-gut microbiota1. Most of the knowledge of microbiota present in sandflies of the New World was carried out with Lutzomyia longipalpis (Lutz and Neiva), vector of American visceral leishmanias...

Heterogeneity of Association Between MTHFR and Stroke Among European Regions: Additional Population Studies Are Needed in Italy To the Editor: The recent meta-analysis of Cronin et al1 examined the association between the MTHFR C677T polymorphism, the strongest genetic determinant of moderate hyperhomocysteinemia, and ischemic stroke. These authors considered 31 studies, including 15 from Europ...

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal plasma cell dyscrasia characterized by the presence monoclonal immunoglobulin, in absence multiple myeloma (MM) or any related lymphoplasmacytic malignancies.1 There recently accepted term—monoclonal clinical (MGCS)—used order to describe gammopathies that do not meet diagnostic criteria for symptomatic MM, but d...

Global developmental delay and intellectual disability are relatively common pediatric conditions. This report describes the recommended clinical genetics diagnostic approach. The report is based on a review of published reports, most consisting of medium to large case series of diagnostic tests used, and the proportion of those that led to a diagnosis in such patients. Chromosome microarray is...

Global developmental delay and intellectual disability are relatively common pediatric conditions. This report describes the recommended clinical genetics diagnostic approach. The report is based on a review of published reports, most consisting of medium to large case series of diagnostic tests used, and the proportion of those that led to a diagnosis in such patients. Chromosome microarray is...

in a fellow-eye-controlled trial, we compared the posterior capsule opacification (pco) rates of single-piece (sa60at) and three-piece (ma60ac) hydrophobic acrylic intraocular lenses (iol) in 54 pair-matched eyes of 27 age-related cataract patients who consecutively underwent bilateral (4-8 weeks apart) phacoemulsification horizontal chopping performed through a capsulorrhexis of approximately ...

The Engineering Integrity Society (EIS) has been a valuable forum for practicing engineers and scientists from the international fatigue durability community since its foundation in 1985. Fatigue 2021 was eighth series of major conferences organized by EIS, Society's first online, on-demand event. principal theme conference to explore discuss challenges using high-performance materials reliable...