Abstract Hypercholesterolemia is correlated with cardiovascular diseases. The search for effective alternatives lipid-lowering drugs continuous. We investigated the hypocholesterolemic activity of Bassia muricata methanolic extract (BMME) in a model hyperlipidemia. B. was extracted methanol. Male rats were randomly divided into six groups: normal control group (G1) fed diet, negative (G2) high ...

Abstract Background The plant Culcasia angolensis (Araceae) has diverse ethnomedicinal uses, including the management of rheumatic pain, healing cuts, dislocations, and bruises. Despite its potential therapeutic toxicity profile not been evaluated. This study assessed sub-acute effects leaves extract (CAE). phytochemical determination CAE was conducted as per standard protocols. median lethal d...

Pulsed Fourier transform proton magnetic resonance spectroscopy was used to study the glutamatealanine transaminase-catalyzed incorporation of deuterium from solvent deuterium oxide into the cy and p positions of L-alanine. It was found that the /3 proton resonance signal initially disappears slightly faster than the signal due to the LY proton, but whereas the o( proton signal decays exponenti...

Background Liver ischemia/reperfusion (I/R) injury is a complex and multifactorial pathophysiological process. It well recognized that the membrane permeability transition pore (mPTP) opening of mitochondria plays crucial role in cell death after I/R injury. Cyclophilin D (CypD) critical positive regulator mPTP. However, effect CypD on pathogenesis liver whether potential therapeutic target are...

The effects of stocking density on growth performance, serum biochemistry, digestive enzymes, immune response, and muscle quality largemouth bass (Micropterus salmoides) reared in nine in-pond raceway systems (IPRS, 22.0 m × 5.0 2.0 m) were studied. M. salmoides with initial an body weight 8.25 ± 0.51 g length 6.99 0.44 cm at 90.91 ind./m3 (low density, LSD), 113.63 (middle MSD), 136.36 (high H...

Despite their rarity and physiologically neutral character, more inherited structural variants of serum albumin (alloalbumins) are known than for any other human protein except hemoglobin. Including three previously unreported examples described here, we have identified 13 different point substitutions in alloalbumins of Japanese origin. Of these only albumin B and two proalbumins have been rep...

Twenty four patients of classical marasmus and kwashiorkor along with equal number of healthy controls were selected for the study. Their serum amino acid patterns analysis revealed a mean ratio of glutamate to alanine in fasting samples of normal individuals to be 0.33, while it as 9.3 in kwashiorkor and 1.6 in marasmus. This differences in controls, kwashiorkor and marasmus was statistically ...

1. Lactation is associated with an increase in the arterial blood concentration of L-alanine and L-glutamate, but a decrease in that of L-glutamine compared with the corresponding values for virgin rats. 2. Virgin rats fed a 'cafeteria diet' that induces hyperphagia have increased arterial concentrations of L-alanine, L-glutamate and L-glutamine. During lactation L-alanine and L-glutamate conce...