BACKGROUND The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain and impaired vision. In pigmented retinal pigment epithelium (RPE), dihydroxyphenalanine (L-Dopa), an intermediate in the synthetic path for melanin, has been hypothesized to regulate the tempo of neurogenesis. The time course o...

the aim of this study was to determine the combination effect of latanoprost and pilocarpine on theintraocular pressure and pupil size in normal rabbits. in this study, 18 rabbits were randomized to threegroups of 6 animals each. the right eyes of rabbits in group 1 were treated topically with latanoprost, ingroup 2 with pilocarpine and in group 3 with latanoprost and pilocarpine. the left eyes...

camel milk has an importance in the treatment of diabetes. it has been shown that the patients who drink camel milk daily, their need to insulin decrease. therefore, this study aimed to investigate the effect of camel milk in comparison with insulin treatment in experimentally-induced diabetes. this study was carried out on forty male new zealand rabbits, divided into four groups with ten rabbi...

objective: for many years in herbal medicine the antihypertensive and lowering blood lipid properties of achillea wilhelmsii (a. wilhelmsii) have been suggested. in the present study the impacts of the plant extract on rabbit’s blood pressure and heart rate have been investigated. materials and methods: twelve nwz rabbits weighed 2-3 kg were randomly divided into two groups of 6 rabbits. the te...

background: effects of estrogen on bone metabolism and its protective role on prevention of osteoporosis are well   documented. however, the efficacy of estrogen treatment on bone healing is not well investigated. the drug can be delivered both systemically or locally to the bone with differences in concentrations and side effects. the aim of this study was to investigate the effect of local an...

in rabbits, especially in some races, limb movement disorder called splay legs, are mostly unilateral or bilateral in front or hind legs at an early age. the severity ranges from mild to severe in this case. in breeding colony of albino dutch laboratory rabbits, the splay leg disorder has been observed over the years permanently.within the scope of this research, 1.5-2.5% of 700-750 number of c...

The domestication process of the laboratory rat has been going on for several hundred generations in stable environmental conditions, which may have affected their physiological and behavioural functions, including their circadian system. Rats tested in our ethological experiments were laboratory-bred wild Norway rats (WWCPS), two strains of pigmented laboratory rats (Brown Norway and Long Evan...

Behavioral, anatomic, and electrophysiologic studies indicate that the nondecussated optic system is functionally incompetent and anatomically disorganized in albino animals. The number of nondecussated optic nerve fibers from the retina to the lateral geniculate nuclei, pretectal nuclei, and superior colliculi is significantly reduced in albino mammals, and the laminae of the dorsal lateral ge...

The behaviour of the albino and melanic variants of Biomphalaria glabrata of Belo Horizonte (MG. Brazil) was studied comparatively, in terms of their respective susceptibilities to infection by Schistosoma mansoni of the same origin, through observation of the elimination of cercariae for a three-month period and the calculation of mortality and infection rates, in control and in infected snail...

BACKGROUND AND AIMS Potassium, sulphur and zinc contents of mistletoe leaves are generally higher than in their hosts. This is attributed to the fact that chemical elements which are cycled between xylem and phloem in the process of phloem loading of sugars are trapped in the mistletoe, because these parasites do not feed their hosts. Here it is hypothesized that mutant albino shoots on otherwi...