Research Alerts is a service provided to you by the Institute for Work & Health (IWH) to help you keep abreast of recent literature in the areas of occupational health and safety, epidemiology, public health and others within the IWH mandate. Please note that these articles have not been reviewed by Institute scientists to assess the quality of the studies. Research Alerts should not be conside...

BACKGROUND Although alert fatigue is blamed for high override rates in contemporary clinical decision support systems, the concept of alert fatigue is poorly defined. We tested hypotheses arising from two possible alert fatigue mechanisms: (A) cognitive overload associated with amount of work, complexity of work, and effort distinguishing informative from uninformative alerts, and (B) desensiti...

OBJECTIVE This study tested the hypothesis that lactate testing in ED sepsis patients could be increased using a computer alert that automatically recognizes systemic inflammatory response syndrome (SIRS) criteria and recommends lactate testing in cases of sepsis defined as ≥2 SIRS criteria plus physician suspicion of infection. Secondary outcomes included the effect of the alert on lactate tes...

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OBJECTIVES To determine what information can be helpful in prioritizing and presenting medication alerts according to the context of the clinical situation. To assess the usefulness of different ways of delivering medication alerts to the user. DESIGN An international Delphi study with two quantitative rounds. 69 researchers with expertise in computerized physician order entry (CPOE) systems ...

Background: The rapid diagnosis of mycobacterial infections is essential to implement the adequate antimicrobial therapy. This study evaluates the performance of the BacT/ALERT 3D system for isolates and identification of mycobacteria from clinical samples. Methods: 1011 clinical specimens from nonsterile and sterile body sites were studied from August 2010 to December 2012 at the National Refe...

Rapid diagnostic pathways for cancer have been implemented, but evidence whether shorter diagnostic intervals (time from primary care presentation to diagnosis) improves survival is lacking. Using the Clinical Practice Research Datalink, we identified patients diagnosed with female breast (8,639), colorectal (5,912), lung (5,737) and prostate (1,763) cancers between 1998 and 2009, and aged >15 ...

A method for detecting a trend change in a multiregional epidemic is developed for a standard epidemiological SIR compartment model and a meta-population network model. The method is applicable to the investigation of the efficacy of the implemented public health intervention from a time series of the number of new cases reported in multiple geographical regions. The change point of the probabi...

Alert Fusion is a process of combining alerts from multiple Intrusion Detection Systems to make a decision about the presence of attack or intrusion. A reliable decision from an alert fusion requires that Intrusion detectors involved in the fusion process generates fully reliable alerts. The unreliable alerts from intrusion detectors may completely misleads the decision making process. The exis...

A new formulation of clomazone (the active ingredient in Command herbicide) was evaluated at four locations in 2010. The trade name of this product is Alert® and it was developed by Cheminova. The level of crop response and barnyardgrass control observed with Alert was similar to that of Command herbicide. Furthermore the rate structure and level of control observed by soil type appears to be t...