The polychlorinated biphenyl congener 2,3,4,5,6-pentachlorobiphenyl and hexachlorobenzene were reductively dechlorinated in an aqueous biomimetic model system containing vitamin B12. The products of 2,3,4,5,6-pentachlorobiphenyl dechlorination were 2,3,5,6- and 2,3,4,6-tetrachlorobiphenyl. Hexachlorobenzene dechlorinated to pentachlorobenzene and a mixture of 1,2,4,5- and 1,2,3,5-tetrachloroben...

cate that cellular deoxyribonucleic acid (DNA) might be the primary and perhaps the critical site of alkylation by cytotoxic alkylating agents (21). The biologic systems used in most of these investigations, however, have not permitted a direct correlation between alkylation of DNA and the observed biologic effects; that is, there is a lack of evidence whether alkylation of DNA is essential to ...

Abstract. General theoretical approach, based on projection operator techniques and scattering theory, applied to the electron transport through flexible molecular bridge is reviewed and explained within a simple model describing a biphenyl molecule connected between two metal leads. Transmission probability through the bridge and its current-voltage characteristics are calculated in one electr...

Alkylation of beta-amino ester enolates proceeds with high diastereoselectivity. Single crystal, powder, and solution X-ray diffraction studies of the enolate show that the racemic enolate forms prismatic hexamers. 6Li NMR spectroscopic studies on partially racemic enolates reveal complex mixtures of homo- and heterochiral hexamers. An implicit fit of the aggregate populations to the Boltzmann ...

Two new inclusion compounds of 9,9'-spirobifluorene (SBF) incorporating benzene [(I), C25H16.C6H6] and biphenyl [(II), C25H16.C12H10], and a new polymorph of SBF [(III), C25H16] are reported. All three exhibit C-H...pi(arene) hydrogen bonds between adjacent SBF molecules. Compound (II) also contains biphenyl C-H to SBF pi-arene interactions. Collectively, hydrogen bonding gives rise to a chain ...

Five polychlorinated biphenyl (PCB)-degrading bacteria were tested for the ability to differentiate between the enantiomers of four atropisomeric PCB congeners (2,2',3,6-tetra-CB; 2,2',3,3',6-penta-CB; 2,2',3,4',6-penta-CB; and 2,2',3,5',6-penta-CB) after growth in the presence of tryptone-soytone, biphenyl, carvone, or cymene. Enantioselectivity was shown to vary with respect to strain, congen...

By employing aerobic oxidation to aldehydes as a more effective alcohol activation strategy, ligand-free copper catalysts were found to be superior catalysts than other metals in aerobic dehydrative β-alkylation of secondary alcohols and α-alkylation of methyl ketones using alcohols as the green alkylating reagents. Based on our mechanistic studies and also supported by the literature, we deduc...