background: periodontitis and rheumatoid arthritis (ra) share a number of clinical and pathologic features, one of which is the presence of the tumor necrosis factor alpha (tnf-α)-induced bone resorption that is involved in the pathogenesis of both. objectives: to investigate the effect of tnf-α blockade on periodontal conditions in patients with active ra. method: the periodontal statuses of 3...

background: use of hormone replacement therapy (hrt) may increase the risk of adult-onset asthma in women. various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic mediators which was not observed in estrogen receptor-alpha (er-alpha) knockout mice. thus, estrogen might be a key element in occurrence of asthma. in the present study, we p...

introduction increase in alpha band is observed when blood perfusion in frontal area of head decreases. the present study evaluated some changes in the alpha band particularly, alpha-1 of frontal and central areas of the head, when several areas were exposed simultaneously to magnetic field. materials and methods five points of head (f3, f4, cz, t3, and t4) of twenty healthy male participants w...

pterygium is characterized by an elastic degeneration of the conjunctiva that extends across the limbos and invades the cornea. the recurrence rate is varied from 25-80% after primary closure to 6% with free conjunctival and iimbal grafts. several adjunctive therapies have been investigated for recurrent pte¬rygium. this article presents a 52-year-old athletic man who was seen for evaluation of...

objective diabetes mellitus is manifested by hyperglycaemia. different treatments such as diets and drugs are recommended for diabetes control. for various reasons in recent years traditional plant (herbal) therapies as prescribed by indigenous systems of medicine with different mechanisms have commonly been used. the digestive enzymes such as alpha glucosidase are among these herbal remedies. ...

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background: alpha thalassemia (α-thal) is one of the most common hemoglobinopathies worldwide. the aim of this study was to investigate the spectrum of α-thal mutations among premarital baluch couples in southeastern iran. subjects and methods: we assessed 1215 individuals by multiplex gap polymerase chain reaction (gap-pcr) and amplification refractory mutation system (arms-pcr). results: of t...

conclusions the current study adds evidence to the association of tnf-α gene polymorphism and ms in this southern south iranian population which is consistent with the genetic analysis of ms in europeans (games) project reports and these two alleles reported in this study may be one of the genetic risk factor for ms. furthermore, this data can be used to build the iranian gene bank for future s...

background tnf-α is one of the most potent cytokines in proinflammatory reactions. results one hundred and twenty children with acute pyelonephritis were evaluated. urinary tnf-α/cr was 0.0051 ± 0.00083 pg/g creatinine. the authors found out a significant difference in urinary tnf-α/cr between patients who have normal and abnormal levels of urine leukocytes, urine protein, urine culture, erythr...