Objective(s): Recognized as a distinguished environmental and global toxicant, Bisphenol A (BPA) affects the liver, which is a vital body organ, by the induction of oxidative stress. The present study was designed to investigate the protective effect of quercetin against BPA in hepatotoxicity in Wistar rats and also, the activity of mitochondrial enzymes were evaluated...

Aim of the study: To establish effectiveness discrete plasmapheresis in treatmentof patients with nonalcoholic fatty liver disease accompanied by hyperferritinemia andconcomitant obesity.Material and methods. The study is based on clinical observations 18 patientswith non-alcoholic steatohepatitis concomitantobesity. Each patient was undergoing basic therapy as well sessions discreteplasmaphere...

The effect of Laennec, a hydrolyte of human placenta, on immune-mediated liver injury was investigated in vivo and in vitro in murine. Vena caudalis administration of concanavalin A (Con A) was employed to establish an in vivo liver-injury model, and in vitro hepatotoxicity was induced by 8 h interaction between Con A pre-treated hepatocytes and Con A-stimulated autologous splenic lymphocytes. ...

OBJECTIVE To investigate injury pattern during intense exercises in hot and humid environment particularly on liver in a rat exertional heat stroke model. METHODS We randomly divided 30 rats into a control group (CG), a normal temperature (25±2°C, 60%±5% humidity) exercise group (NTEG) and a high temperature and high humidity (35±2°C, 80%±10% humidity) exercising group (HTEG), each comprising...

 Background & Objective:  Overweight people are more vulnerable to developing fatty liver disease, moreover; they are more likely to have increased serum liver enzymes and lactate dehydrogenase than others. The aim of this study was to evaluate the changes in liver enzymes and lactate dehydrogenase after doing exhaustive aerobic and anaerobic exercises in active overweight male students.  Mate...

The current study was done to investigate the preclinical safety and toxicology of Althaea officinalis extract as naturopathic medicine in common carp (Cyprinus carpio). Specimens were treated with 0 (control), 2.5, 5 and 10 g of marshmallow extract for 45 days. Plasma biochemical parameters were measured after 15 and 45 days. Total protein, albumin and globulin levels (p<0.05) &nbsp;were signi...

We investigated whether hepatic artery endothelium may be the earliest site of injury consequent to liver ischemia and reperfusion. Twenty-four heartworm-free mongrel dogs of either sex exposed to liver ischemia/reperfusion in vivo were randomized into four experimental groups (N = 6): a) control, sham-operated dogs, b) dogs subjected to 60 min of ischemia, c) dogs subjected to 30 min of ischem...

Fifteen crocodiles were randomly divided into three groups of five animals. They represented high-infection, medium-infection and low-infection groups of 642 larvae/kg, 414 larvae/kg and 134 larvae/kg bodyweight, respectively. The parameters assessed were blood glucose, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), aspartate transaminase (AST) and alanine transaminase (ALT). The hu...

objective: we used sodium nitroprusside (snp), a nitric oxide (no) releasing molecule, to understand its effect on viability and proliferation of rat bone marrow mesenchymal stem cells (bm-mscs). materials and methods: this experimental study evaluated the viability and morphology of mscs in the presence of snp (100 to 2000 µm) at 1, 5, and 15 hours. we chose the 100, 1000, and 2000 µm concentr...

Data on infiltrative hepatocellular carcinoma (iHCC) receiving hepatectomy are unclear. Our study assessed the outcomes, effects of anatomical resection, and prognostic factors in a cohort of Chinese patients with iHCC undergoing hepatectomy.Data from 47 patients with iHCC undergoing hepatectomy were analyzed in a retrospective study. Independent prognostic factors of overall survival (OS) and ...