Although both asthmatics and allergic rhinitics develop an acute inflammatory response to lower airway allergen challenge, only asthmatics experience airway obstruction resulting from chronic environmental allergen exposure. Hypothesizing that asthmatic airways have an altered response to chronic allergic inflammation, we compared the effects of repeated low-level exposures to inhaled Alternari...

natural plant extracts / products have the potential as safe alternatives for chemical fungicides in plant disease management. methanol and pure methanol: water (50:50 v/v) extracts of peppermint, lavandula, eucalyptus, datura and nettle were screened for their antifungal activity against alternaria sesami, the causal agent of alternaria leaf spot of sesame at 5, 10 and 15% concentrations in sh...

Alternaria and Cladosporium spores belong to the most frequent and allergenic particles in bioaerosol in the temperate climate. The investigation of Alternaria and Cladosporium spore concentrations was performed in two cities in Poland, Szczecin and Cracow, in 2004-2013. The meteorological parameters taken to assess their impact on fungal spores were average, maximum and minimum temperature, re...

INTRODUCTION Agricultural producers are exposed to a number of different health risks associated with their work environment. AIM The objective of the study was to assess the degree of colonization by fungi in terms of quantity and in terms of variety of species the samples taken from the settled dust from combine threshing of rye cultivation from organic and conventional farms in the Provinc...

UNLABELLED BACKGROUND Petroleum pollution is a global disaster and there are several soil cleaning methods including bioremediation. METHODS In a field study, fugal strains were isolated from oil-contaminated sites of Arak refinery (Iran) and their growth ability was checked in potato dextrose agar (PDA) media containing 0-10% v/v crude oil, the activity of three enzymes (Catalase, Peroxid...

A gene for the Alternaria major allergen, Alt a 1, was amplified from 52 species of Alternaria and related genera, and sequence information was used for phylogenetic study. Alt a 1 gene sequences evolved 3.8 times faster and contained 3.5 times more parsimony-informative sites than glyceraldehyde-3-phosphate dehydrogenase (gpd) sequences. Analyses of Alt a 1 gene and gpd exon sequences strongly...

BACKGROUND Genome-wide association studies have identified the ORM (yeast)-like protein isoform 3 (ORMDL3) gene locus on human chromosome 17q to be a highly significant risk factor for childhood-onset asthma. OBJECTIVE We sought to investigate in vivo the functional role of ORMDL3 in disease inception. METHODS An Ormdl3-deficient mouse was generated and the role of ORMDL3 in the generation ...

Sexual reproduction in heterothallic ascomycete fungi is controlled by a single mating-type locus called MAT1 with two alternate alleles or idiomorphs, MAT1-1 and MAT1-2. These alleles lack sequence similarity and encode different transcriptional regulators. A large number of phytopathogenic fungi including Alternaria spp. are considered asexual, yet still carry expressed MAT1 genes. The molecu...

Alternaria, dünyada yaygın olarak görülen önemli bir fungus cinsi olup Ascomycota bölümü, Dothideomycetes sınıfı, Pleosporales takımı ve Pleosporaceae familyasında yer almaktadır. Alternaria içerisinde, saprofitik, endofitik patojenik türler Patojen arasında ise bitki patojenleri, hasat sonrası patojenler veya insan patojenleri de bulunmaktadır. spp. Alternariol (AOH), monometil eter (AME), Ten...