INTRODUCTION The most widely used protocol for the induction of experimental allergic airway inflammation in mice involves sensitization by intraperitoneal (i.p.) injections of the antigen ovalbumin (OVA) used in conjunction with the adjuvant aluminium hydroxide (alum). Although adjuvants are frequently used, there are questions regarding the necessity of alum for murine asthma studies due to t...

Background: well water provide that comes from a layer of soil is relatively close to the ground surface, therefore it easily exposed contamination through seepage. In general, seepage human excreta, latrines or and animals, as waste itself, either because floor sewerage are not impermeable water. The condition construction way drawn can also be source contamination, for example wells with open...

The use of biodegradable polymer matrices as a single-dose vaccine delivery system was investigated using tetanus toxoid (TT) and diphtheria toxoid (DT). BALB/c mice were immunized with TT or DT in different formulations including individual, in minipellet and aluminum hydroxide (alum), and the antibody responses were monitored for 48 weeks. Antigens entrapped in minipellet elicited higher anti...

The used of antibiotics to control bacterial growth has a negative impact such as resistance. Began look for alternative materials from nature, including saponins, flavonoids, catechins and tannins which are known be contained in the roots Tawas Ut (Ampelocissus rubiginosa Lauterb). This plant been empirically by people Central Kalimantan, namely medicine wounds diarrhea. efficacy alum root not...

The adjuvant potential of two mesoporous silica nanoparticles (MSNs), SBa-15 and SBa-16, was assessed in combination with a recombinant HSP70 surface polypeptide domain from Mycoplasma hyopneumoniae, the etiological agent of porcine enzootic pneumonia (PEP). The recombinant antigen (HSP70212-600), previously shown as immunogenic in formulation with classic adjuvants, was used to immunize BALB/c...

BACKGROUND Silica particles cationized by dioctadecyldimethylammonium bromide (DODAB) bilayer were previously described. This work shows the efficiency of these particulates for antigen adsorption and presentation to the immune system and proves the concept that silica-based cationic bilayers exhibit better performance than alum regarding colloid stability and cellular immune responses for vacc...

Background: Controlling parenchymal hemorrhage especially in liver parenchyma, despite the progress in surgical science, is still one of the challenges that surgeons face when trying to save patients’ lives. Researchers in the field are challenging to introduce a more effective method. Objectives: The current study aimed to determine the haemostatic effect of alum [KAl (SO4)2] and compare it wi...

Amending poultry litter with Al sulfate (alum) has proven effective in reducing water-soluble P in the litter and in runoff from fields that have received litter applications. Although its effectiveness has been demonstrated on a macroscopic scale in the field or in the poultry houses, little is known about P speciation in either alum-amended or unamended litter. This knowledge is important for...

Background: Recurrent aphthous stomatitis (RAS) is the most common painful ulcers of oral mucosal which can cause many sufferings. Treatment of RAS often includes administration of corticosteroids, analgesics and regulators of the immune system. However, considering the side effects of these medications, even their topical application must be done with caution. Alum is used in traditional medic...