brachystegia eurycoma is predominantly grown in the eastern region of nigeria. its seed is used in food majorly as a soup condiment, flavouring agent and soup thickener. the proximate, mineral and amino acid compositions were determined on raw and processed seeds (boiled, fermented and roasted) using standard analytical techniques. the processing methods showed deviations in nutrients from the ...

in recent years considerable interest has been focused on the plasma amino acid patterns as a possible index of protein malnutrition, in children. thus a change in the ratio of non-essential to essential amino acids is considered to be significant in the development of protein malnutrition. the present paper reports a simplified and rapid chromatographic procedure for the determination of this ...

Angiotensin II (ANG II) promotes vascular smooth muscle cell (VSMC) growth, stimulates Ca(2+)-calmodulin (CaM)-dependent kinase II (CaMKII), and activates cytosolic Ca(2+)-dependent phospholipase A2 (cPLA2), which releases arachidonic acid (AA). ANG II also generates H2O2 and activates Akt, which have been implicated in ANG II actions in VSMC. This study was conducted to investigate the relatio...

Serum amyloid A proteins (SAA), presumed precursors of the tissue amyloid A proteins (AA) characteristic of secondary amyloidosis, have been isolated from the plasma high-density lipoproteins (HDL) of normals after etiocholanolone-induced inflammation and from patients with Wegener's granulomatosis, systemic lupus erythematosis, juvenile rheumatoid arthritis, Waldenström's macroglobulinemia, an...

Herein, we report on the synthesis and characterization of ruthenium compounds with general formula [RuCl(AA-H)(NO)(dppb]PF6, where AA = glycine (1), L-alanine (2), L-phenylalanine (3) L-valine (4), dppb 1,4-bis(diphenylphosphine)butane. The complexes were characterized using elemental analysis, UV/Vis infrared spectroscopies, 1H, 13C, 31P NMR techniques, cyclic voltammetry. Furthermore, struct...

In most prokaryotes Asn-tRNA and Gln-tRNA are formed by amidation of aspartate and glutamate mischarged onto tRNA and tRNA, respectively. Coexistence in the organism of mischarged Asp-tRNA and Glu-tRNA and the homologous Asn-tRNA and Gln-tRNA does not, however, lead to erroneous incorporation of Asp and Glu into proteins, since EF-Tu discriminates the misacylated tRNAs from the correctly charge...

Human breast milk (BM) amino acid (AA) composition may be impacted by lactation stage or factors related to geographical location. The present cross-sectional study is aimed at assessing the temporal changes of BMAA over lactation stages in a large cohort of urban mothers in China. Four hundred fifty BM samples, collected in three Chinese cities covering eight months of lactation were analyzed ...

Positron emission tomography using radiolabeled amino acid (PET-AA) appears to be promising in distinguishing between recurrent tumour and radionecrosis in the follow-up of brain metastasis (BM). The amino acid transporter LAT1 and its cofactor CD98, which are involved in AA uptake, have never been investigated in BM. The aim of our study was to determine and compare the expression of LAT1 and ...

Amino acid (AA) analysis in plasma is essential for diagnosis and monitoring of inborn errors metabolism (IEM). The efficacy patient management governed by the rapidity AA profile availability, along with robustness method. French quality guidelines progress made analytical techniques have led biologists to develop exploration via mass spectrometry (MS). aim this study was validate an method a ...

Peptide-bond modification via N-hydroxylation has been explored as a strategy for metal coordination to induce conformational rigidity and orient side chains for specific molecular recognition. N-Hydroxyamides were prepared by reacting N-benzyloxyamino acid esters or amides with Fmoc-AA-Cl/AgCN (Fmoc: 9-fluorenylmethoxycarbonyl; AA: amino acid) in toluene or Fmoc-AA/HATU/DIEA in DMF (HATU: O-(7...