Entomopathogenic nematode formulation technology has made significant progress in the past 15 years. Formulations ranging from the impregnation of nematodes on artificial sponge to highly advanced granular formulations have been developed. Major challenges have included the development of room-temperature shelf stability, ease of use, and contamination control. Enhanced storage stability has be...

Bioactive compounds contained in the seed kernel and other parts of the neem tree (Azadirachta indica A. Juss) have been found to show insecticidal activities and other effects in many species of insects. These activities include antifeedancy, growth regulation, fecundity suppression, male sterility, oviposition repellency, changes in biological fitness such as loss of flying ability, immunodep...

Tylosin, a drug mainly used in veterinary medicine, belongs to the macrolide group of antibiotics. In this study the bioequivalence and differences in pharmacokinetics of solution and powdered tylosin formulations were established. The following recommended by EMEA parameters: Cmax, Tmax, AUC were determined. All the investigations were carried out in the populations of 74 broilers chickens. Th...

The inhibitory function of Dimilin (Diflubenzuron), mostly a chitin synthesis regulator, on the ecdysis of mosquitoes (Anopheles gambiae s.l., Culex quinquefasciatus) and housefly was evaluated in the field and in laboratory. Three formulations of Diflubenzuron were evaluated in this study: Dimilin, Wettable powder (25%), Dimilin granules (2%), and Dimilin tablets (2%). The laboratory and field...

The study was undertaken to evaluate some chemical parameters of powder milk available in Mymensingh town. Powder milk samples of six different brands namely Kwality, NIDO, Diploma, Anchor, Farmland & Starship were collected from local market. Powder samples were analyzed to know the chemical (P, acidity, fat, protein, lactose, ash, moisture, solids-not-fat, total solids) characteristics. P, ac...

The trend among pharmaceutical companies to develop selective drugs of high potency has pushed the industry to consider the potential of each hazardous ingredient to become airborne. Dustiness issues are not unique to the pharmaceutical industry, but are relevant to any industry where powdered materials are mixed, transferred and handled. Interest in dustiness is also driven by concerns for wor...

INTRODUCTION FDA-approved antibiotics with known safety and efficacy in humans, normally delivered orally or by injection, include rifampicin, aminoglycosides, and cephalosporins for treating tuberculosis, influenza, brucellosis, tuleremia, and anthrax. These drugs are proposed for inhalation delivery for treatment and as a first-line defense against spread of the disease. Advantages include: (...

The pharmacokinetic (PK) and pharmacodynamic (PD) profile of an antimicrobial agent provides important information that can be used to maximize bacteriologic and clinical efficacy, minimize selective pressure for the development of antimicrobial resistance, and determine an optimal dosing regimen. Judicious selection of an antimicrobial based on local susceptibility data and PK and PD parameter...

The present study was designed to develop and evaluate the nutritional, functional, sensory properties texture profile data of garlic peel powder fortified viz. 2%, 5% 10% value added pukhelein compared with control sample. Garlic showed crude fiber, carbohydrate ash content 60.57%, 21.71% 16.34%, total phenolic (TPC) 108.79 µg/ml GAE, flavonoid (TFC) 33.27 mg Quercetin/ml antioxidant activity ...

the most frequent adverse effects of indomethacin like other nsaids are gastro–intestinal and central nervous system disturbances. extended release or enteric release formulations minimize these symptoms. the objective of this study was to develop an extended release pellet formulation of indomethacin by the centrifugation (rotary fluid bed granulation) or powder layering method. layered, nonpa...