نتایج جستجو برای: ampc β

تعداد نتایج: 178420  

2013
J. Kamile Rasheed Brandon Kitchel Wenming Zhu Karen F. Anderson Nancye C. Clark Mary Jane Ferraro Patrice Savard Romney M. Humphries Alexander J. Kallen Brandi M. Limbago

We characterized 9 New Delhi metallo-β-lactamase-producing Enterobacteriaceae (5 Klebsiella pneumoniae, 2 Escherichia coli, 1 Enterobacter cloacae, 1 Salmonella enterica serovar Senftenberg) isolates identified in the United States and cultured from 8 patients in 5 states during April 2009-March 2011. Isolates were resistant to β-lactams, fluoroquinolones, and aminoglycosides, demonstrated MICs...

Journal: :Antimicrobial agents and chemotherapy 2011
Pierre Bogaerts Andrea M Hujer Thierry Naas Roberta Rezende de Castro Andrea Endimiani Patrice Nordmann Youri Glupczynski Robert A Bonomo

A new commercial low-density microarray which identifies common extended-spectrum β-lactamase plasmid-mediated cephalosporinase genes, as well as carbapenemase (bla(KPC) and bla(NDM)) genes, was evaluated. We tested 207 clinical and reference/collection isolates of the Enterobacteriaceae possessing different bla genes. Overall, the sensitivity and specificity of the microarray were 100% for the...

2015
Guy Prod'hom Christian Durussel Dominique Blanc Antony Croxatto Gilbert Greub

Bacterial pellets from Enterobacteriaceae positive blood cultures prepared using ammonium chloride were tested for rapid detection of β-lactamase using the commercial βLACTA test and read after 30 minutes. During 7 months, 137 bacterial pellets were tested prospectively. βLACTA test exhibited a sensitivity of 75% and a specificity of 100% for the detection of third-generation cephalosporin resi...

2012
Hajime Kanamori Hisakazu Yano Yoichi Hirakata Ayako Hirotani Kazuaki Arai Shiro Endo Sadahiro Ichimura Miho Ogawa Masahiro Shimojima Tetsuji Aoyagi Masumitsu Hatta Mitsuhiro Yamada Yoshiaki Gu Koichi Tokuda Hiroyuki Kunishima Miho Kitagawa Mitsuo Kaku

The incidence of extended-spectrum β-lactamases (ESBLs) has been increasing worldwide, but screening criteria for detection of ESBLs are not standardized for AmpC-producing Enterobacteriaceae such as Enterobacter species. In this study, we investigated the prevalence of ESBLs and/or AmpC β-lactamases in Japanese clinical isolates of Enterobacter spp. and the association of plasmid-mediated quin...

2014
Jing Zhang Beiwen Zheng Lina Zhao Zeqing Wei Jinru Ji Lanjuan Li Yonghong Xiao

BACKGROUND In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county hospitals. METHODS E. coli isolates were collected from patients with community-onset infections in 30 county hospitals. ESBL activity was confirmed by double-disc diffusi...

Journal: :The Journal of antimicrobial chemotherapy 2010
Rikke Lind Jørgensen Jesper Boye Nielsen Alice Friis-Møller Hans Fjeldsøe-Nielsen Kristian Schønning

OBJECTIVES To establish the prevalence of the AmpC beta-lactamase phenotype in clinical isolates of Escherichia coli and characterize the genetic resistance mechanisms causing the observed phenotype. METHODS Clinical E. coli (n = 74) with reduced susceptibility to third-generation cephalosporins and resistance to cefoxitin were collected from the Department of Clinical Microbiology at Hvidovr...

2017
Yi-Wei Huang Yu Wang Yun Lin Chin Lin Yi-Tsung Lin Cheng-Chih Hsu Tsuey-Ching Yang

Penicillin binding proteins (PBPs) are involved in peptidoglycan synthesis, and their inactivation is linked to β-lactamase expression in ampR-β-lactamase module-harboring Gram-negative bacteria. There are seven annotated PBP genes, namely, mrcA, mrcB, pbpC, mrdA, ftsI, dacB, and dacC, in the Stenotrophomonas maltophilia genome, and these genes encode PBP1a, PBP1b, PBP1c, PBP2, PBP3, PBP4, and ...

2013
Takehisa Chuma Daisuke Miyasako Hesham Dahshan Tomoko Takayama Yuko Nakamoto Francis Shahada Masato Akiba Karoku Okamoto

Epidemiologic surveillance study was conducted in southern Japan to determine the antimicrobial resistance phenotypes and characterize the β-lactamase genes and the plasmids harboring these genes in Salmonella enterica serovar Infantis (S. Infantis) isolates from broilers. Between January, 2007 and December, 2008, a total of 1,472 fecal samples were collected and examined at the Laboratory of V...

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