This paper represents an experimental analysis of crosssensitivity, which is the main problem that usually faces one of the most important glucose sensors which is the amperometric enzyme electrode. The elimination of cross-sensitivity is based-on experimental determination of correction factors. Moreover, the solution for biocompatibility problem is discussed. Then, these solutions were electr...

We have synthesized polyacrylamide-polypyrrole (PPy/PA) microparticles which present conductivity in the range of the semiconductor materials (around 10 S/cm). Glucose Oxidase was immobilized within microparticles with composition 50/50 (w/w) PPy/PA. These microparticles were used as biological component of an amperometric biosensor which shows similar glucose response in both aerobic and anaer...

Carbon nanotubes are regarded as promising building blocks for the construction of novel biosensors due to their unique properties like fast electron transfer, high electrocatalytic effect and good biocompatibility. In the present study, the effect of different chemical oxidation’s methods of multi-walled carbon nanotubes (MWCNTs) on the electrochemical behavior of modified graphite electrodes ...

For an efficient flow battery operation, knowledge of the state charge is essential. Monitoring both half cells advantageous concerning a timely detection crossover processes. We present first results for amperometric and electrochemical quartz crystal microbalance measurements in vanadium test setup. By validating with cell potential as well ex situ titration we investigate applicability metho...

with amperometric detection. It has been shown elsewhere that the selectivity of this method is sufficient to separate the potential organic impurities; that is, synthesis byproducts and a specified degradation product from the drug substance (3). The objective of this article is to demonstrate that this method’s suitability for stability testing can be evaluated easily by performing HPLC with ...

Direct, selective, rapid and simple determination of organophosphate pesticides has been achieved by integrating organophosphorus hydrolase with electrochemical and opitical transducers. Organophosphorus hydrolase catalyzes the hydrolysis of a wide range of organophosphate compounds, releasing an acid and an alcohol that can be detected directly. This article reviews development, characterizati...

The electrical contacting of redox enzymes with electrodes is the most fundamental requirement for the development of amperometric biosensors and biofuel cell elements. For the effective electrical communication of redox enzymes with electrodes the use of electron relay units that transport the electrons between the enzyme redox center and the conducting surface is essential. Also, the structur...

We report here on a facile enzymatic polymerization protocol to prepare enzyme-poly(thiophene-3-boronic acid) (PTBA) polymeric biocomposites (PBCs) for high-performance mono-/bi-enzyme amperometric biosensing. Horseradish peroxidase (HRP)-catalyzed polymerization of thiophene-3-boronic acid (TBA) monomer was conducted in aqueous solution containing HRP (or plus glucose oxidase (GOx)) by either ...

Cover picture: Schematic of amperometric detection of exocytosis at a neuroendocrine cell. iii To Mike and Julia iv v ABSTRACT Exocytosis is the universal basis for neuronal communication, allowing the controlled release of neurotransmitter molecules from the presynaptic cell. Exocytosis has been widely studied in many systems. However, the details of this vital process are not fully understood...

The Cover Feature illustrates a quadruple immunoplatform for the amperometric determination of blood protein candidate biomarkers (NfL, Tau, p-Tau and TDP-43) to assist in reliable minimally invasive Alzheimer′s disease diagnosis. cover was drawn by Beatriz Arévalo co-designed with authors. More information can be found Research Article A. Valverde, J. M. Gordón Pidal et al.