Cystic tumors of the pancreas account for less than 10% of pancreatic neoplasms. Intraductal papillary mucinous carcinomas (IPMNs) account for 21-33% of these tumors. IPMNs represent papillary neoplasms within the main pancreatic duct and/or side branches showing mucin hypersecretion that often leads to duct dilation and chronic obstructive pancreatitis [1]. A 55-year-old patient presented with...

We report the case of a periampullary collision tumor, in which a duodenal-wall carcinoid and an adenocarcinoma of the head of the pancreas coexisted. We describe the case of a 64-year-old man with a recent history of diarrhea, who was diagnosed with obstructive jaundice. A duodeno-pancreatectomy was performed, and the specimen showed two independent neoplasms in the histopathologic study. Soli...

Endoscopic resection is used to treat duodenal lesions [1]. However, the rate of perforation in the duodenum is relatively higher than that in other areas, and such perforation can be fatal [2]. Polyglycolic acid (PGA) sheets can be used to prevent delayed perforation after endoscopic submucosal dissection (ESD) in the duodenum [3], and to cover a delayed perforation after gastric ESD [4]. Howe...

Duodenal duplication cysts are rare congenital malformations. Most symptomatic cases are diagnosed in children and usually present with obstructive findings or bleeding symptoms. Treatment traditionally involves surgical resection, which can be often difficult because of the close proximity of the cysts to the papilla and bilopancreatic confluence. Endoscopic therapy has been used as an alterna...

Ampullary adenocarcinoma (A-AC) is a rare malignancy arising from the ampulla of Vater. KRAS mutation is detected in 30-40% of patients with A-AC, but its clinical implication and prognostic value are not well described. We conducted this meta-analysis to investigate the association between KRAS mutation and prognosis in patients with A-AC. We searched Pubmed, MEDLINE, EMBASE, and the Cochrane ...