Introduction: Study was taken with an objective to investigate the inhibitory effect of Phaseolus lunatus seeds extract on three enzymes (α-amylase, maltase and glucoamylase) which are involved in diabetes. The disadvantages related use synthetic drugs make it necessary search for alternative from medicinal plants. One therapeutic approach treatment postprandial hyperglycaemia is decrease plasm...

Kandelia candel, a mangrove belonging to the family Rhizophoraceae, whole plant is reported have anti-diabetic properties and was studied for evaluation of in vitro antioxidant antidiabetic study. Total Phenolic Content (TPC), Flavonoid (TFC) Alkaloid were quantitatively estimated by using standard protocols. The study evaluated activity extract method employed are DPPH radical scavenging assay...

The nano sized copper oxide material (CuONPs) were prepared by the greener way and an approach functionalized polymer using Sarcostemma acidum stem extracts. in-vitro anti-diabetic activity was studied through α-glucosidase α-amylase inhibitory methods demonstrated in stem, biological synthesized CuONPs polymerized CuONPs. percentage inhibition at 100 μg/ml, 200 300 400 μg/ml 500μg/ml concentra...

In this study, the copper nanoparticles were synthesized using various concentrations (5%, 6 %, 8%, and 10%) of Nigella sativa seed extracts, their antibacterial antiobesity effect was evaluated. The optimum particle size (98.23 nm) obtained at an extract concentration 8%. FTIR results confirmed functional groups responsible for ion reduction, exhibited high activity against Pseudomonas aerugin...

Muffin et al. (1), in this issue, describe a more specific method for pancreatic ainylase in serum. Amylase of salivary origin is precipitated with a monoclonal antibody, and the amylase remaining is presumed to come from the pancreas. It is likely that their test will be more specific for pancreatic disease. Since the recognition of multiple sources of antylase and of the frequency of hyperamy...

A cDNA clone that encodes the 14-kDa bifunctional inhibitor from corn seeds (L. Wen et al., Plant Mol. Biol. 18, 813-814, 1992) has been expressed in Escherichia coli after being incorporated into the pT7 expression vector. This inhibitor protein, referred to as CHFI (for the corn inhibitor of activated Hageman factor) or as the popcorn inhibitor, is an important tool for specific inhibition of...

Inhibition of α-amylase and α-glucosidase, advanced glycation end products (AGEs) formation, and oxidative stress by isolated active constituents of Osmanthus fragrans flowers (9,12-octadecadienoic acid and 4-(2,6,6-trimethyl-1-cyclohexenyl)-3-buten-2-one) and their structural analogues were evaluated. 9,12-Octadecadienoic acid was 10.02 and 22.21 times more active against α-amylase and α-gluco...

Objective: To evaluate the alpha amylase inhibitory activity of different extract of bark of Albizia lebbeck (L.) Benth. Methods: Bark of A. lebbeck was collected and air dried. Extraction of flavonoid, alkaloid and steroid carried out using standard methods. Extracts in different polar and non polar solvents were extracted using soxhlet method. Filtered extracts were subsequently tested for al...