Background: The calamondin (Citrus microcarpa Bunge) and the kumquat (Fortunella crassifolia Swingle) are two small-size citrus fruits that have traditionally been consumed in Taiwan; however, there has been a lack of scientific research regarding the active compounds and functionalities of these fruits. Methods: Analysis of volatile composition of essential oil and phytosterol was carried out ...

Several enzymes of plant sterol or triterpenoid biosynthesis involve during their catalysis postulated or demonstrated carbocationic high energy intermediates. It has been demonstrated previously that the design of transition state or high energy intermediate analogues could lead to powerful and specific inhibitors of enzymes. The aim of the present study was to interfere with plant sterol or t...

Because of the present pandemic researchers are seeking for phytocandidates that can inhibit or stop SARS-CoV-2. The main protease (Mpro) SARS-CoV-2 and spike glycoprotein (S) both suppressed by bioactive compounds found in plants work docking them together. Mpro proteins 6LU7 (complex with an inhibitor N3) 5C3N (space group C2221) were employed research. PyRx AutoDock Vina software used as eng...

To evaluate possible new drugs for the treatment of Colorectal Carcinoma (CRC) using in silico tools was main objective this study. The method analysis used evaluation tumor markers and their interaction with selected drugs, through study its pharmacokinetic pharmacodynamic characteristics. A potential therapeutic target pointed out Cell Division Cycle 25 B (CDC25B), belonging to CDC25 phosphat...