نتایج جستجو برای: an important animal model prepared
تعداد نتایج: 7232851 فیلتر نتایج به سال:
Source localization in the human brain based on EEG and MEG data becomes more and more important in the field of clinical research and routine. Thus, information about source localization accuracy is indispensable. Source localization accuracy has been tested with various artificial source and volume conductor models. However, there are a number of limitations inherent to these artificial model...
Although the existence of a link between neurodegenerative diseases and obesity has been suggested, a causal relation between neural degeneration and obesity has remained to be demonstrated experimentally. We recently showed that neurodegeneration in the hypothalamic satiety center results in obesity in mice transgenic for E4B (also known as UFD2a), a mammalian ubiquitin elongation factor (E4)....
The learning of rich associative networks is foundational to language and other advanced cognitive competencies. Such learning is commonly encouraged by direct supervision entailing explicit feedback for correct and incorrect responses. The power of explicit feedback has recently been demonstrated in an animal model (Wasserman, Brooks, & McMurray, 2015), in which pigeons successfully learned to...
1. Efforts to understand the links between evolutionary and ecological dynamics hinge on our ability to measure and understand how genes influence phenotypes, fitness and population dynamics. Quantitative genetics provides a range of theoretical and empirical tools with which to achieve this when the relatedness between individuals within a population is known. 2. A number of recent studies hav...
Objectives: Lallemantia royleana (Benth. in Wall.) Benth. (Lamiaceae) is a medicinal plant used in Iranian traditional and folklore medicine in the treatment of various nervous, hepatic, and renal diseases. In the present study, whole seeds of the herb were prepared and evaluated for hypolipidemic activities using an animal model. Materials and Methods: Animals were fed normal diets or diets su...
PURPOSE This study attempted to define an optimum animal model for neonatal thoracoscopy. MATERIALS AND METHODS Seven rabbits and three 5-7-kg piglets were subjected to thoracoscopy by three pediatric surgeons. The outcome for the successful completion of esophageal anastomosis and additional procedures, including diaphragmatic plication and lung biopsy, were noted. RESULTS Whereas esophage...
Medulloblastoma (MB) is the most common malignant brain tumor in children. Patients whose tumors exhibit overexpression or amplification of the MYC oncogene (c-MYC) usually have an extremely poor prognosis, but there are no animal models of this subtype of the disease. Here, we show that cerebellar stem cells expressing Myc and mutant Trp53 (p53) generate aggressive tumors following orthotopic ...
PURPOSE Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for the treatment of many joint disorders, inflammation and to control pain. Numerous reports have indicated that NSAIDs are capable of producing nephrotoxicity in human. Therefore, the objective of this study was to evaluate mefenamic acid, a NSAID nephrotoxicity in an animal model. METHODS Mice were dosed intraperitoneally with ...
objectives: lallemantia royleana (benth. in wall.) benth. (lamiaceae) is a medicinal plant used in iranian traditional and folklore medicine in the treatment of various nervous, hepatic, and renal diseases. in the present study, whole seeds of the herb were prepared and evaluated for hypolipidemic activities using an animal model. materials and methods: animals were fed normal diets or diets su...
one way to confront chemical warfare in order to reduce their harmful effects, is to use the body's defense mechanisms. in order to do so firstly mustard gas (hd) was injected in an animal model in the form of an immunogen and the induced humoral immune response was investigated by two different immunological methods such as the ouchterlony test and a new liquid phase fluoroimmunoassay. 7l...
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