introduction: evaluation of the cerebrospinal fluid (csf) white blood cell (wbc) count and glucose and protein concentrations is used to assess the probability of the presence of central nervous system (cns) infection. although normal values are well established for csf cell counts and protein and glucose contents in children and adults, this is not the case for neonates. the purpose of this st...

Background We evaluated the cost-effectiveness of nivolumab versus everolimus in patients with advanced renal cell carcinoma (RCC) from a US payer perspective. Methods A partitioned survival model consisting of three health states, progression-free survival (PFS), progressive disease, and death, was developed to evaluate the cost-effectiveness of intravenous nivolumab versus oral everolimus o...

This study sought to examine the extent which age at first substance use contributes later addiction severity and how PTSD affects their relationships. The enrolled 315 patients from tertiary services in Rwanda. participants’ mean was 18.64 years (SD = 6.1) old. Age had a significant effect (β − 0.130, p .013) on severity. showed association with 0.363; < .001). variance explained by increased ...

BACKGROUND Arterial proteoglycans are implicated in the pathogenesis of atherosclerosis by their ability to trap plasma lipoproteins in the arterial wall and by their influence on cellular migration, adhesion and proliferation. In addition, data have suggested an anti-atherogenic role for heparan sulfate proteoglycans and a pro-atherogenic role for dermatan sulfate proteoglycans. Using a non-hu...

BACKGROUND Respiratory syncytial virus (RSV) is an established cause of serious lower respiratory disease in children, but the burden in adults is less well studied. METHODS We conducted a retrospective study of hospitalizations among adults ≥20 years from the 1997-2012 National Inpatient Sample. Trends in RSV admissions were described relative to unspecified viral pneumonia admissions. Hospi...

PURPOSE Obesity is an independent risk factor in trauma-related morbidity in adults. The purpose of this study was to investigate the effect of obesity in the pediatric trauma population. METHODS All patients (6-20 years) between January 2004 and July 2007 were retrospectively reviewed and defined as non-obese (body mass index [BMI] <95th percentile for age) or obese (BMI > or =95th percentil...

Marrow cells from 36 patients with myelodysplastic syndromes (MDS) (13 refractory anemia [RA], 14 refractory anemia with excess of blasts [RAEB], 9 RAEB in transformation [RAEB-T]) were evaluated for their in vitro proliferative and differentiative responsiveness to recombinant human granulocyte colony-stimulating factor (G-CSF) or granulocyte-monocyte CSF (GM-CSF). GM-CSF exerted a stronger pr...

conclusions in patients with severe preeclampsia undergoing cesarean delivery, a continuous iv infusion of nitroglycerine was able to attenuate the cardiovascular response to intubation to a greater extent than the use of sublingual nifedipine or iv hydralazine, without significant adverse effects on the newborn. results in contrast to those in group nif and group h, the patients in group ntg s...