THE major broad achievements by the luminaries concept of genetic load (Haldane 1937; Muller 1950; Crow 1993). Other essays in the Perspectives series that of science often distract from our appreciation of their significant but narrower contributions to allied refer to Muller are Paul (1988), Lederberg (1991), Crow (1992), and Crow and Abrahamson (1997). fields. One example is Linus Pauling’s ...