The majority of endocrine disruption studies in Europe have been on non-indigenous species (some of them tropical!)--and none of which has traits that make them suitable for the detection of androgenic compounds. To overcome these problems, we have been developing the stickleback as a model biomarker for testing the effect of endocrine disrupters in European waters. Its advantages are: it is th...

Fungal growth can be influenced by human physiological mediators such as androgenic hormones. The aim of this study was to investigate a possible relationship between androgenic hormones and susceptibility to dermatophytosis. To this purpose we measured the levels of testosterone, androstendione, and dehydroepianderosterone sulfate (DHEA-S) in 60 male patients with dermatophytosis due to Epider...

The crustacean male-specific androgenic gland (AG) regulates sexual differentiation. In the prawn Macrobrachium rosenbergii, silencing an AG-specific insulin-like encoding transcript (Mr-IAG) inhibited the development of male sexual characters, suggesting that Mr-IAG is a key androgenic hormone. We used recombinant pro-Mr-IAG peptide to generate antibodies that recognized the peptide in AG cell...

This study surveyed 28 athletes competing at a regional mixed martial arts (MMA) event. The survey attempted to gather information regarding overall training volume, supplement use, and specific exercises used. The survey return rate was 100% (28/28). Twenty-five out of the 28 athletes supplemented their training with strength training. Overall frequency of strength training sessions/week range...

The auditory system exhibits differences by sex and by sexual orientation, and the implication is that relevant auditory structures are altered during prenatal development, possibly by exposure to androgens. The otoacoustic emissions (OAEs) of newborn male infants are weaker than those of newborn females, and these sex differences persist through the lifespan. The OAEs of nonheterosexual female...

UNLABELLED Since 1959, when Norman Orentreich described the phenomenon of donor dominance in androgenic alopecia and opened the way to hair transplantation, the field of hair replacement surgery has been evolving continuously. Advances in the last 15 years, particularly the microscopic dissection of donor strips into follicular units, have eradicated the idea that follicular transplantation is ...

An 81-year-old man, admitted with lumbago and pollakisuria, was diagnosed to have stage D2 prostate cancer (T3N2M1). Although the serum level of prostate specific antigen (PSA) was 3,560 ng/ml, serum testosterone (55.6 ng/dl) and luteinizing hormone (LH, 0.8 mIU/ml) levels were very low. Detailed inquiry of the patient revealed a daily intake of patent medicine containing 6-9 mg methyltestoster...

Androgenic hormones induce inhibition or regression of the bursa of Fabricius in the chick embryo. The high doses of hormones necessary to this involution raises the question of the processes involved and their putative role in the normal development of the bursa. If androgens play a role it is mediated by receptor sites in target cells. Using an autoradiographic technique, receptor sites for a...

AIMS To analyse correlates of anabolic androgenic steroids (AAS) use in the general male population. DESIGN A national household survey. PARTICIPANTS Individuals aged 15-64 years in Sweden. MEASUREMENTS AAS use and potential correlates of AAS use, including demographic data, financial situation, physical training, and substance use. In hierarchical logistic regression analyses, lifetime u...

BACKGROUND Considering the recent popularity of bodybuilding and the apparent spread of anabolic androgenic steroid (AAS) use amongst bodybuilding enthusiasts in Kuwait, there is a relative lack of scientific investigation into the use, knowledge and attitudes towards AAS amongst the population at risk of abusing it. Therefore, this study aims to investigate the frequency, knowledge, attitudes ...