At the time of an initial public offering, shares in a firm are typically held by venture capitalists, insiders, corporate investors, and angel investors. We examine the role of angel investors in the IPO process. We find that angel investors provide equity capital in industries that venture capitalists are less likely to serve and that shareholders in angel backed IPO firms are more likely to ...

A novel fractal called Fractal Clover Leaf (FCL) is introduced and shown to have well miniaturization capabilities. The proposed patches are fed by L-shape probe to achieve wide bandwidth operation in PCS band. A numerical parametric study on the proposed antenna is presented. It is found that the antenna can attain more than 72% size reduction as well as 17% impedance bandwidth (VSWR<2), in co...

Alfredo Pironti began by explaining that they had found they could exploit Web application logic by disrupting TLS by closing the connection. For example, a wire transfer to “Charlie%27s_ Angels” could become one for “Charlie” if the packet were fragmented after “Charlie” and the connection closed before the second packet was sent. Pironti said that the solution was as simple as correctly desig...

Based on a sample of 539 angel investors, we empirically test the impact of new ventures’ resource acquisition/allocation strategies in different development stages on angels’ abnormal returns and their extremeness. Our findings suggest that at earlier stages, ventures whose entrepreneurs focus more on securing new resources tend to not only give angel investors lower abnormal returns, but also...

In recent years, the relevance of the immune system to fight cancer has led to the development of immunotherapy, including the adoptive cell transfer of immune cells, such as natural killer (NK) cells and chimeric antigen receptors (CAR)-modified T cells. The discovery of donor NK cells' anti-tumor activity in acute myeloid leukemia patients receiving allogeneic stem cell transplantation (allo-...

Submit Manuscript | http://medcraveonline.com related cost has increased consistently [3]. At the moment, there are six biological agents licensed by FDA for the treatment of CD (infliximab, adalimumab, golimumab, certolizumab, vedolizumab, and natalizumab, the last two being an anti-α4β7 and anti-α4β1integrin, respectively), and three for UC (infliximab, adalimumab, and vedolizumab), whereas t...

Unfortunately, men are not angels and administration is an important tool to provide internal and external controls. Madison (1787b) states that assuming any form of government can secure liberty or happiness without any virtue in the human being is an imaginary idea. The virtue, in fact, should be used to select the rulers. The selection of the rulers who will be exact protectors of the public...

A key regulator of proliferation, differentiation and cell fate, the c-Myb transcription factor regulates the expression of hundreds of genes and is in turn regulated by numerous pathways and protein interactions. However, the most unique feature of c-Myb is that it can be converted into an oncogenic transforming protein through a few mutations that completely change its activity and specificit...