نتایج جستجو برای: anthracyclines
تعداد نتایج: 3200 فیلتر نتایج به سال:
The class II anthracycline antitumor antibiotics musettamycin, rudolfomycin, aclacinomycin and marcellomycin, which were shown in earlier studies to preferentially inhibit the synthesis of nucleolar RNA in intact tumor cells, were studied in an isolated nucleolar transcriptional assay. Their effects were compared with those of the nucleolar non-selective anthracyclines adriamycin, carminomycin ...
Anthracyclines are the mainstay of treatment of a variety of haematological malignancies and solid tumours. Unfortunately, the clinical use of these drugs is limited by cumulative, dose-related cardiotoxicity which may ultimately lead to a severe and irreversible form of cardiomyopathy. Thus, there is an increasing need for close cooperation among cardiologists, oncologists and haemato-oncologi...
cardiotoxicity is one of the most important adverse event related to anthracycline therapy and can lead in about 1-5% of cases to the occurrence of heart failure. in a higher percentage of patients treated with these drugs asymptomatic left ventricular dysfunction can occur, so that guidelines recommend a strict clinical and echocardiographic monitoring. however, the occurrence of left ventricu...
Introduction Chemotherapy-induced alopecia (CIA), although reversible, is one of the most common and distressing side effects cancer therapy, affecting approximately 65 percent all patients influencing treatment decisions in some them. Scalp cooling (SC) a method aiming to prevent CIA. Our study aims evaluate real value SC devices. Methods A systematic review available scientific literature on ...
Previous studies suggest cardiac imaging in cancer patients for detection of cancer-therapy-related dysfunction (CTRCD) is discordant with international guidelines, clinical implications unknown. Cancer were recruited prior to either anthracyclines or trastuzumab administration and underwent concurrent strategy Multigated Acquisition Scan (MUGA)-based timing determined by treating oncologist, e...
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