نتایج جستجو برای: anti antipruritic
تعداد نتایج: 362950 فیلتر نتایج به سال:
recent studies have indicated the profound anti-tumor activity of artemisinin's compounds, among which; arteether is an oil-soluble derivative of artemisinin with an endoperoxide bridge that can induce apoptosis in tumor cells but not in the normal cells. an experiment was carried out on tumor-bearing balb/c mice to estimate the effects of arteether on tumor growth and antitumor im...
hyalomma marginatum is a hard-bodied tick found on animals. this tick has been implicated in the transmission of bahig virus, a pathogenic arbovirus previously thought to be transmitted only by mosquitoes.
nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...
هدف از این مطالعه این است که آیا بیماری هپاتیت b و درمان با اینترفرون آلفا تاثیری در مقادیر پلاسمایی پارامترهای t3 ، t4، tsh و آنتی بادی anti-tpo دارد یا خیر؟ هپاتیت b از بیماریهای خطرناک ویروسی بوده و طی آن آسیب زیادی به کبد و دیگر اعضا می رسد. در این مطالعه 10 مورد مبتلا به هپاتیت b (درسنین و جنس مختلف) و10 مورد سالم (از نظر بالینی وآزمایشگاهی ) مورد بررسی و مطالعه قرار گرفتند. پس از تشخیص ب...
Chronic itch in atopic dermatitis is a significant clinical problem with unmet needs. Pain also common symptom of dermatitis. Crisaborole, PDE-4 inhibitor, approved for the treatment mild to moderate The inhibitor appears reduce by activating cAMP-PKA pathway. However, mechanism underlying this antipruritic effect has not fully understood. mouse model was developed repeatedly applying MC903. Cr...
purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...
Primary sensory neurons in the dorsal root ganglia and trigeminal ganglia are responsible for sensing mechanical and thermal stimuli, as well as detecting tissue damage. These neurons express ion channels that respond to thermal, mechanical, or chemical cues, conduct action potentials, and mediate transmitter release. These neurons also express a large number of G-protein coupled receptors, whi...
UNLABELLED Central serotonin (5-hydroxytryptophan, 5-HT) modulates somatosensory transduction, but how it achieves sensory modality-specific modulation remains unclear. Here we report that enhancing serotonergic tone via administration of 5-HT potentiates itch sensation, whereas mice lacking 5-HT or serotonergic neurons in the brainstem exhibit markedly reduced scratching behavior. Through phar...
Generalised pruritus occurs in 25-50/ of cases of polycythaemia vera. Neither the cause nor the most effective treatment has been established. A relation with iron deficiency has been suggested and relief after iron treatment recorded.' Cholestyramine has been reported to have an antipruritic action in polycythaemia vera, which might imply an association with raised concentrations of conjugated...
BACKGROUND Canine flea-allergy dermatitis (FAD), a hypersensitivity response to antigenic material in the saliva of feeding fleas, occurs worldwide and remains a common presentation in companion animal veterinary practice despite widespread availability of effective systemic and topical flea-control products. HYPOTHESIS/OBJECTIVES To evaluate the clinical response in dogs with FAD treated top...
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